Antidiabetic Agents
The most likely ADE from a blood glucose agent.
What is hypoglycemia?
Not enough can lead to weakened bones, muscle weakness, and decreased energy levels.
What is phosphorus?
Found in kidney beans, black beans, bananas, and clams.
What is potassium?
Too much can cause flushing of the skin, itching, nausea, and upset stomach.
What is niacin (Vitamin B3)?
The antidote for warfarin overdose.
What is vitamin K?
First line treatment for type II diabetes.
What is metformin?
Bonus 100 points
What drug class is metformin?
Not enough can lead to bleeding gums, fatigue, joint pain, and poor wound healing.
What is Ascorbic Acid (vitamin C)?
Found in cashews, pumpkin seeds, green leafy vegetables, and walnuts.
What is magnesium?
Too much can cause nausea, GI upset, abdominal cramps, as well as headache, fatigue, and easy bruising.
What is vitamin E?
Type of vitamins that are more likely to lead to toxicity.
What are fat soluble vitamins (Vitamin D, Vitamin A, Vitamin E, Vitamin K)?
Semaglutide and exenatide
What is GLP-1 Agonists?
Not enough can cause rickets and osteomalacia.
What is Calcifediol, Cholecalciferol,
Ergocalciferol (Vitamin D)?
Found in pork, oatmeal, beans and other whole grains.
What is thiamin (vitamin B1)?
Too much can cause loss of appetite, weight loss, excessive thirst, excessive urination, dehydration, constipation, and anorexia.
What is vitamin D?
The antidote for magnesium toxicity.
What is calcium gluconate?
Common DDI for all blood glucose agents.
What are other blood glucose agents?
Not enough can lead to muscle cramps and palpitations. This can never be given IV push.
What is potassium?
Found in almonds, fish, sunflower oil, and pine nuts.
What is vitamin E?
Too much can cause nausea, kidney stones, and heart arrhythmias.
What is calcium?
Method to reduce lipodystrophy.
Duration of action is 24 hours.
What is long acting insulin (glargine)? or What is NPH?
Not enough can cause Wernicke-Korsakoff syndrome which is linked with alcoholism.
What is Thiamine (Vitamin B1)?
Found in dairy, cereal, salmon, and tuna.
What is Calcifediol, Cholecalciferol,
Ergocalciferol (Vitamin D)?
Bonus 100 points
What mineral does Vitamin D help the body absorb?
Too much causes cracked fingernails, bone pain, loss of appetite, cracked corners of the mouth, blurry vision, and liver damage.
What is vitamin A?
Signs include clammy skin, weakness, hunger, tachycardia, and inability to concentrate.
What is hypoglycemia?