Which characteristic improves a drug’s ability to reach the central nervous system (CNS)?
Lipid solubility
A postoperative patient has an epidural infusion of morphine sulfate [Astramorph]. The patient’s respiratory rate declines to 8 breaths per minute. Which medication would the nurse anticipate administering?
Naloxone [Narcan]
The nurse assesses a patient who takes ibuprofen [Advil] on a regular basis. Which finding does the nurse know is an adverse effect of ibuprofen [Advil] therapy?
Hematemesis
When administering prednisone to a patient, the nurse will do what?
Ensure that meals are at bedside so that administration with food reduces gastric irritation.
A nurse administers naloxone [Narcan] to a postoperative patient experiencing respiratory sedation. What undesirable effect would the nurse anticipate after giving this medication?
Increased pain
A patient has an infection affecting a central nervous system (CNS) component. Which structure makes the delivery of antibiotic therapy more difficult?
Blood-brain barrier
The nurse is planning care for a patient receiving morphine sulfate [Duramorph] by means of a patient-controlled analgesia (PCA) pump. Which intervention may be required because of a potential adverse effect of this drug?
Inserting a Foley catheter
A patient is scheduled to start taking aspirin for the treatment of rheumatoid arthritis. The nurse anticipates that which medication most likely will be prescribed?
Pantoprazole [Protonix]
The nurse is developing a plan to minimize the risk of adrenal insufficiency for a patient who is receiving long-term glucocorticoid therapy. Which outcome should be included?
Increases or supplements dosage of glucocorticoid at times of stress
What does the nurse identify as possible complications of glucocorticoid therapy? (Select all that apply.)
Impaired carbohydrate and glucose tolerance
Increased production of glucocorticoids from the adrenals
Predisposition to gastrointestinal ulceration
Decrease in serum sodium and glucose levels
Impaired carbohydrate and glucose tolerance Correct
Increased production of glucocorticoids from the adrenals
Predisposition to gastrointestinal ulceration Correct
Decrease in serum sodium and glucose levels
Which neurotransmitter is active in both the peripheral and central nervous systems (CNS)?
Norepinephrine
A patient takes oxycodone [OxyContin] 40 mg PO twice daily for the management of chronic pain. Which intervention should be added to the plan of care to minimize the gastrointestinal adverse effects?
The patient should increase fluid and fiber in the diet
A nurse teaches a patient who takes daily low-dose aspirin for protection against myocardial infarction and stroke to avoid also taking which medication?
Ibuprofen [Motrin]
A patient is receiving glucocorticoids for the treatment of rheumatoid arthritis. The patient complains of having a headache. Which ordered medication should the nurse administer?
Acetaminophen [Tylenol]
A nurse instructs the parent of a child with influenza that which medication or medications may be used safely to reduce fever?
Acetaminophen [Tylenol]
The nurse is caring for a patient with depression who takes citalopram [Celexa], an antidepressant. The nurse understands that the full therapeutic effects are not seen until about 3 to 4 weeks after beginning this drug. What is the best description of this process?
Adaptive changes in the brain
Which agent is most likely to cause serious respiratory depression as a potential adverse reaction?
Morphine [Duramorph]
A nurse should recognize that a patient who takes an angiotensin-converting enzyme (ACE) inhibitor while also taking high-dose aspirin is at risk of developing what complication?
Renal failure
A patient takes glucocorticoids and digoxin [Lanoxin]. It is most important for the nurse to monitor which electrolyte?
Potassium
A patient who has rheumatoid arthritis is scheduled to start taking celecoxib [Celebrex]. A nurse should recognize which factor from the patient’s history as a contraindication to taking this medication?
Recent heart bypass surgery
The nurse is working with a group of patients receiving drugs that work in the central nervous system (CNS). Nursing care of these patients is based on which facts? (Select all that apply.)
Overall knowledge of the workings of CNS agents is limited.
The CNS has many more neurotransmitters than the periphery.
Animal studies in progress will greatly enhance knowledge of CNS medications.
When CNS drugs are taken long term, their effects differ from initial use.
The blood-brain barrier is permeable to water-soluble drugs.
Overall knowledge of the workings of CNS agents is limited. Correct
The CNS has many more neurotransmitters than the periphery. Correct
Animal studies in progress will greatly enhance knowledge of CNS medications.
When CNS drugs are taken long term, their effects differ from initial use. Correct
The blood-brain barrier is permeable to water-soluble drugs.
The nurse is working on a postoperative unit in which pain management is part of routine care. Which statement is the most helpful in guiding clinical practice in this setting?
The development of opioid dependence is rare when opioids are used for acute pain.
A nurse provides discharge instructions for a patient who is taking acetaminophen [Tylenol] after surgery. The nurse should instruct the patient to avoid which product while taking acetaminophen?
Alcoholic drinks
The nurse should question an order for glucocorticoids in the treatment of a patient with what?
Systemic fungal infection
The nurse is screening a patient before administering a live virus vaccine. The patient is currently taking a glucocorticoid medication. Which action should the nurse take?
Note the contraindication and clarify the order with the healthcare provider