Potassium, Calcium, Phosphates, and Magnesium
Pathogenesis of Azotemia
Urinalysis
Anatomy & Upper UTI clinical disorders
Blood Gas & Acid-Base
100

Which parasite has the potential to cause Pseudo-Addison's?

What are Whipworms (Trichuris vulpis). 

100

What are the three types of Azotemia? And give an example of all 3.

What is Pre-renal (decrease blood flow), Renal (nephron damage) and Post-renal (urinary obstruction).

100

What is the only proteinuria that causes hypoalbuminemia?

What is glomerular proteinuria

100

This structure in the bladder is the dorsal triangular area located within lines connecting the ureteral openings in the bladder. What is the gross internal feature called?

What is the Trigone

100

What happens to the amount of chloride ions when a patient is vomiting?

A: Chloride ions are lost in vomit or sequestered with hydrogen ions due to the increase in HCO3- = Metabolic Alkalosis

200

What is a suspicious ratio for addison's? Hint the Na:K ratio

What is an Na:K = 20

200

A dog is dehydrated and the USG is 1.010. What type of Azotemia is this?

What is Renal Azotemia

200

An alkaline pH will cause ___ crystals. These type of crystals are very common in dogs and cats and are usually caused by UTI's.

What are Struvites

200

Look at image on Brandt's Ipad. What is the arrow pointing to?

What is ureteral papilla

200

What is the difference between organic and inorganic metabolic acidosis?

A: 

Inorganic: due to kidney problem, kidneys not excreting H+ like they should

Organic: Increased production of H+ from ketones or lactate

300
What is the pathogenesis of hypokalemic disorders? Is K+ going in or out of the cell?

What is increase renal loss, Increase K+ secretion.

What is K+ shift into cells (maintain electroneutrality)

300

Azotemia and a USG of <1.035 is indicative of what disease?

Hint: Cats

What is CKD.

300

What is your TOP differential if the urinalysis detects red urine, negative sediment, 2+ protein, and your patient is anemic? Bonus: Is it pre-renal, renal, or post-renal?

What is Intravascular hemolytic Anemia. (IMHA is the overall term)

300

Ingestion of this will lead to tubular degeneration and obstruction. Also is the most common intoxication in dogs and cats

What is Ethylene glycol (antifreeze)

300

What is respiratory response to metabolic acidosis and how does this compensate?

A: Hyperventilation, blows out CO2 which decreases H+ in blood because CO2 dissociates into H+ ions

400

Where is fCa2+ and fMg2+ reabsorbed? And what hormone is it dependent on?

Hint: fCa2+ is reabsorbed in two locations.

What is the ascending LOH (fCa2+ and fMg2+), and distal nephron (fCa2+)

Hormone: PTH

400

What are differences between Glomerular Disease and Tubular disease? Give me two differences minimum for each disease. 

G: 1. Lost Albumin in urine. 2. UPC usually >>1.0. 3. Possible Azotemia

T: 1.WRI Albumin usually reabsorbed. 2. UPC usually <<1.0. 3. +/- glucosuria

400

What 2 conditions will you see false positive heme on a urinalysis and will look like hemoglobinuria is present?

What is dilute and alkaline urine causes RBC's to lyse

400

What stain is used for Glomerular Amyloidosis?

What is Congo Red Stain

400

How would you classify a patient's blood gas if they had pH decreased - WNL, PaCO2 increased, HCO3- increased? Name one differential that can cause this?

A: Respiratory acidosis with comp metabolic alkalosis, upper airway obstruction, pleural effusion, infection, sedatives -> anything that blocks the airways/increased capillary gas exchange

500

Hypocalcemia due to chronic kidney disease is a decreased total Ca2+, fCa2+ and Pi which is increasing PTH, What is the secondary cause of this condition?

What is Secondary Renal Hyperparathyroidism.

500

Why do animals lose renal concentrating ability in Chronic Renal Failure?

1. Solute Diuresis - More solute presented to remaining nephrons leads to less water

2. Medullary Hypertonicity is not maintained - Decreased Na+ and Cl- transport in Ascending LOH

3. Distal Tubules less responsive to ADH

500

List the 4 conditions that cause proteinuria and 1 differential for each. 

1. Pre-renal: IMHA, Muscle Necrosis

2. Glomerular: Glomerulonephritis, glomerular amyloidosis

3. Tubular: Acute tubular toxicity (Antifreeze)

4. Post-renal: UTI, Blockage

500

Which nerves to the bladder provide sympathetic, parasympathetic and somatic innervation to the bladder?

Symp: Hypogastric Nerve

Para: Pelvic nerve

Somatic: Pudendal nerve

500

Name one Hypoxia WITH hypoxemia, and name one hypoxia WITHOUT hypoxemia. Describe what those hypoxias are and how they either cause or don't cause hypoxemia. 

Hypoxias -> hypoxemia: Atmospheric, Tidal and Alveolar

Hypoxias w/o -> Hypoxemia: Hemoglobinemic, Stagnant, demand