Glycolysis Reactions
TCA Cycle
Gluconeogenesis
Common Intermediates
Disorders/Dysregulation
100

The end product of glycolysis

Pyruvate
100

Another name for the TCA Cycle

Krebs Cycle, Citric Acid Cycle

100

This is our glucose storage molecule.

Glycogen

100

The interchangeable energy molecule related to ATP

GTP

100

Issues with the pyruvate dehydrogenase complex occur in this subunit.

E1

200

The two phases of glycolysis.

Energy Investment & Energy-Generation

200

The complex responsible for making acetyl CoA

Pyruvate dehydrogenase complex

200

This substrate for gluconeogenesis comes from the hydrolysis of adipose tissue.

Glycerol

200

TPP, lipoic acid, FAD, NAD+, and CoA are all this type of molecule, seen in the PDHC and the alpha-ketoglutarate dehydrogenase complex.

Coenzymes

200

Alpha islet cells release this hormone, which has no effect on the immune system-targeted beta islet cells of people with Type I diabetes.

Glucagon

300

The rate limiting step of glycolysis.

Step 3: Phosphorylation of Fructose 6-phosphate

300

These molecules are released during the TCA cycle.

CO2 and NADH

300

This organelle is where glucose 6-phosphate is turned into glucose.

The ER

300

Related to ATP, this molecule signals that there is low energy, and that glycolysis/respiration must proceed.

ADP

300

Anaerobic glycolysis forms this molecule

Lactate

400

The enzyme that transforms 1,3-BPG into 2,3-BPG.

Bisphosphate mutase

400

The intermediate that is formed during the one of the rate-limiting steps of the TCA, whose precursor was isocitrate.

 alpha-ketoglutarate

400

The bypassing of PFK-1 requires multiple levels of this for gluconeogenesis.

Regulation

400

This molecule is required for gluconeogenesis, also made near the end of glycolysis.

PEP

400

What causes detrimental buildup of pyruvate, inhibiting E1's coenzyme lipoic acid?

Arsenic poisoning

500

These types of enzymes turn glucose into glucose 6-phosphate, trapping it in the cytosol.

Hexokinases

500

This enzyme is complex II of the ETC.

Succinate dehydrogenase

500

OAA must be turned into this molecule to leave the mitochondria

Malate

500

This enzyme is regulated not just by molecules within glycolysis, but also by citrate formed during the TCA cycle.

PFK-1

500

What is the last type of tissue to be broken down into glucose?

Muscle