WEEK 8

MP

100

PDE5 inhibitors are contraindicated with which class of drugs and why?

NO donors - together, NO donors and PDE5 inhibitors can cause severe hypotension. 

200

Which three emergency contraception methods are available in Australia? 

Levonorgestrel tablet, ulipristal acetate tablet, copper IUD 

300

Desmopressin is indicated for what? 

- Diabetes Insipidus (due to ADH insufficiency) 

- Nocturnal enuresis in children 

- Nocturnal polyuria in adults 

400

Which other PDE isoenzymes are inhibited by sildenafil and tadalafil? 

PDE1, PDE3, PDE6, PDE11 

500

Tamsulosin is used to treat benign prostatic hyperplasia and the resulting bladder outlet obstruction. What class does this drug belong to?

Selective alpha blockers - it inhibits alpha-1A adrenoreceptors 

GIMN

100

Which tissue produces chylomicrons? 

The intestine 

200

Which lipoproteins contain 'good' cholesterol and why? 

HDLs - contains excess cholesterol that has been removed from cells and blood that is then transported to the liver for elimination. 

300

Familial hypercholesterolemia is caused by a mutation of which gene on which chromosome? 

LDLR gene on chromosome 19 

400

Which apolipoprotein is responsible for clearing chylomicron remnants in the liver? 

ApoE

500

What are the desirable plasma levels for total LDLs and triglycerides (mmol/L)? 

LDLs: <2.6mmol/L

Triglycerides: <1.7mmol/L

NEURO

100

What are the three auditory ossicles? 

Malleus, incus and stapes 

200

What is the function of the tensor tympani and stapedius muscles in the middle ear? 

Protects the inner ear from loud sounds 

300

In the vestibular pathway, afferent nerves from vestibular hair cells terminate in vestibular nuclei of the medulla. What are these four nuclei called? 

Medial, superior, lateral, inferior 

400

The receptors in the saccule and utricle are sensitive to which types of forces? 

Saccule: vertical forces 

Utricle: horizontal forces 

500

Which three cranial nerves are involved in the sense of taste and where do they carry taste from?

CN VIII (facial nerve): anterior 2/3 of the tongue 

CNIX (glossopharyngeal nerve): posterior 1/3 of the tongue 

CNX (vagus nerve): epiglottis and pharynx 

PMHD

100

At what age does adulthood begin, according to Sawyer? 

25 years 

200

True or false: during adulthood, crystallised intelligence decreases while fluid intelligence increases.

False - crystallised intelligence increases while fluid intelligence decreases.

300

What percentage of mental health presentations are before the age of 25? 

75%

400

What percentage of the Australian population is affected by bipolar at some point in their lives? 

2-5% 

500

In bipolar I disorder, manic episodes last for how long?

At least one week