Bugs and Drugs
Some Like It Hot
Better Call the Plumber
Listen To Your Heart
Potpourri
100

This bacteria is the most common cause of purulent cellulitis

What is Staphylococcus aureus?
100

The Global Initiative for Asthma (GINA) has shifted their recommendation for rescue of an acute asthma attack of any severity to this treatment.

What is inhaled corticosteroids + formoterol?

100

Duration of therapy with proton pump inhibitor for patients with LA Grade C or D esophagitis.

What is indefinite?

100

In addition to traditional cardiovascular risk factors, this test is best able to help risk stratify to predict future cardiovascular events.

What is a calcium score?  
Especially when used with MESA calculator; it can re-classify patients from one risk category to another.

100

The most common cause of macrocytosis without anemia.

What is alcohol use?

200

This medication is most appropriate treatment for clinically stable outpatients with multi-drug resistant E. coli, including resistance to beta-lactams, fluoroquinolones, nitrofurantoin, and trimethoprim-sulfamethoxazole (TMP-SMX)?

What is Fosfomycin?

Often not reported on standard culture sensitivity panels

200

The minimum duration of hormone replacement therapy for someone with premature menopause.

When is until natural age of menopause (approximately age 52)?

200

This drug is superior to proton pump inhibitors for treatment of severe esophagitis and is the first FDA-approved potassium-competitive acid blocker (PCAB).

What is Vonoprazan?

Brand name: Voquezna

200

A type of low density lipoprotein that has been shown to be an independent risk factor for atherosclerotic heart disease and aortic stenosis that the some guidelines recommend checking once in an adult’s life, especially those with premature heart disease.

What is Lp(a) or Lipoprotein A?

200

The only lab parameter (with high quality evidence) that needs to be monitored on testosterone therapy. 

What is hematocrit?

300

The preferred oral outpatient antibiotic treatment for pyelonephritis, especially when using short-courses

What is ciprofloxacin?

300

The preferred initial treatment for acute pericarditis.

What is non-steroidal anti-inflammatory drugs (NSAIDs) + colchicine?

Steroids may have a role in refractory cases, but may increase risk of recurrence.

300

The American Urological Association provides guidance on when to start offering prostate cancer screening with PSA in average risk and high-risk patients - what are these 2 ages?

What is 45 and 40?  

High risk includes black ancestry, germline mutations, strong family history of prostate cancer 

300

An oral medication that can be used in statin intolerant patients, whose mechanism of action is in the liver, that has been shown to reduce the risk of myocardial infarction and coronary revascularization.

What is bempedoic acid?

(Brand name Nexletol)

300

This is a condition in which people with significant vision loss (e.g. from macular degeneration, glaucoma) experience complex, vivid visual hallucinations

What is Charles Bonnet Syndrome?

400

My patient had recurrent Clostridium difficile infection and is at high risk for further recurrence. Aside from fecal microbiota transplant, this monoclonal antibody gives them the best shot at avoiding further recurrence. 

What is bezlotoxumab? 

(Brand name Zinplava)

400

Hormone replacement therapy (HRT) is increasing in popularity to treat bothersome menopausal symptoms.  In a large case-control observational study from Denmark, HRT also increased the incidence of this negative outcome, whose Latin root means without mind.

What is dementia?

400

This 5-hydroxytryptamine 1A (5-HT1A) receptor agonist with FDA-approval for anxiety may help patients with functional dyspepsia by helping to relax the gastric fundus.

What is buspirone?

400

For a patient with permanent atrial fibrillation with persistent tachycardia despite maximal dose of beta-blocker therapy, this drug is most likely to help achieve rate control.

What is digoxin?

400

Lack of this antigen on the surface of red blood cells can cause benign neutropenia and can be easily determined by simple blood antigen testing.

What is Duffy antigen?

Duffy null status is believed to promote egress of neutrophils from circulating blood into tissues, thereby causing neutropenia without increased risk of infections.

500

This drug can reduce the risk of traveler's diarrhea by 50% and may be appropriate for high risk travelers

What is bismuth subsalicylate?

500

This recently approved drug for non-hormonal management of vasomotor symptoms of menopause requires monitoring hepatic function pnael prior to initiation and at 3, 6, and 9 months of therapy.

What is Fezolinetant?

(Brand Name: Veozah)

500

This type of "juice" can help treat muscle cramps in patients with cirrhosis.

What is pickle juice?

500

This landmark trial published in 2023 showed testosterone replacement therapy did not increase risk of major adverse cardiovascular events (MACE) in men with hypogonadism and at risk of cardiovascular disease.

What is the TRAVERSE trial?

(Caveat: The mean (±SD) duration of treatment was 21.7±14.1 months, and the mean follow-up was 33.0±12.1 months.)

500

This formulation of intravenous iron may transiently affect the diagnostic utility of magnetic resonance imaging (MRI).

What is ferumoxytol?

(Brand name Feraheme)