History/Impact
Structure and Bonding
Uses/Applications
Properties
100

Who founded Aspirin? And in what year?

Felix Hoffmann in 1897

100

Does Aspirin’s structure and bonding affect its pain-relieving properties? If so, how?

To be able to relieve pain and inflammation, aspirin’s benzene ring and carboxyl group interact with cyclooxygenase enzymes, to slow down the production of prostaglandins which are responsible for pain and inflammation.

100

Aspirin is an over-the-counter medication, often used to relieve mild pain. What is another name for Aspirin?

Acetylsalicylic Acid (ASA)

100

How does a high melting point affect the uses and applications of Aspirin?

A low melting point in the compound would provide the information that the compound is not 100% pure. If it is not 100% pure, it may not achieve the same effects as 100% aspirin, and could possibly provide negative effects. 

200

What did people use as a pain reliever before Aspirin was founded/created?

Willow bark and other plants containing salicylates have been used for pain relief for centuries.

200

How does the covalent bonds in Aspirin affect the compound?

Aspirin’s covalent bonds keep it stable, which helps the compound be resistant to oxidation and hydrolysis. Being a stable compound that is resistant to breaking down, Aspirin is able to stay on shelves longer and stay effective. The covalent bonds in the molecule keep it stable, making it easier to produce and sell.

200

Aspirin belongs to a class of drugs known as NSAID, what does NSAID stand for?

Nonsteroidal Anti-Inflammatory Drug

200

How does a high boiling point affect the uses and applications of Aspirin?

The boiling point in the compound also can provide the information that the compound is not 100% pure. If it is not 100% pure, it may not achieve the same effects.

300

Who were the ancient physicians that recognized the pain-relieving properties of Aspirin?

Galen and Hippocrates

300

What are the hydrogen bonds in Aspirin bonded too?

In the carboxyl group, the hydrogen atom is bonded to the oxygen atom.  

300

Can Aspirin treat inflammation or muscle aches?

Yes, Aspirin can treat inflammation and muscle aches.

300

Is Aspirin soluble in water? If so, what does the solubility do for Aspirin?

Aspirin is not extremely soluble in water, that’s why you are supposed to take it with lots of water. The solubility of aspirin in water/other substances is important to the use of the compound, as to take aspirin you can dissolve the tablet in water and drink it, or swallow it whole and have it dissolve in your stomach. 

400

What should someone do before taking Aspirin?

They should follow the proper directions on how to use the drug, or contact a healthcare professional.

400

What is the chemical formula of Aspirin?

 The chemical formula of Aspirin is C9H8O4.

400

What helps Aspirin to be able to stay on the shelf for long periods of time?

Its stability (covalent bonds)

400

How does Aspirin's acidic nature affect the use of the product?

Aspirin is a weak acid. The Carboxyl group (COOH) in the salicylic acid portion of Aspirin makes it slightly acidic. The acidic nature of the compound helps it to be dissolved and break down in the acidic environment of the stomach. 



500

When did the pharmaceutical company Bayer name and market Aspirin?

1899

500

What does Aspirin Look like? What is its structure? 

Aspirin’s structure is a flat, planar molecule with a three-dimensional shape.

500

What is Aspirin most commonly used to treat?

Flu-like symptoms like headaches, high temperatures, and sore throats

500

How is Aspirin's stability useful when selling it?

Aspirin is very stable, which helps it to stay on the shelves of stores for a long time. This stability makes it easier to produce and sell Aspirin.