The drugs final elimination from the body's circulation
What is Excretion
100
One of only two methods of drug administration that results in 100% bioavailability.
What is IV Infusion or IV Bolus
100
Most drug absorption occurs in this area of the body.
What is the Small Intestine
100
When administering Cymbalta in patients with slow gastric emptying, should the target dose be increased or decreased?
What is Increased
100
This protein has the ability to reversibly bind drugs on its surface; we know the process as 'protein-binding.'
What is Albumin
200
The sum of all reactions for transformation of substances that take place in the body
What is Metabolism
200
Lilly Neuroscience drug that can be administered by Intra Muscular administration.
What is Zyprexa (Olanzapine)
200
This method of transport fights through gradient to get us the essential vitamins, ions, Amino acids, and glucose that humans need for survival. Drugs are not commonly absorbed this way.
What is Active Transport
200
After five days of taking Cialis 5mg for Once Daily Use, Cmax level is ____ greater than a single dose at peak.
What is 1.6x Greater
200
This 'reflective' calculation is used to predict how a drug will distribute through the body depending on several physiochemical properties (solubility, charge, size etc.)
What is Volume of Distribution (VoD)
300
Loss of drug from the circulation (transfer) into other compartments of the body.
What is Distribution
300
Common sites are deltoid, gluteus, and vastus. Large volume of medication can be absorbed, distribution rate is relatively rapid.
What is Intra Muscular
300
When one or more drugs are competing for absorption, the effects of this 'process' can be synergistic, antagonistic, or produce a new effect that either drug would not produce on their own.
What is a Drug Interaction
300
These Lilly Neuroscience drugs, respectively, are 90%, 98% and 94% protein bound.
What is Cymbalta, Strattera, and Cialis
300
This measurement, taken over a 24-hour period, determines the level of waste product in the blood and urine, and the function of the kidneys.
What is Creatinine Clearance
400
The process of uptake of a drug from the site of administration into the circulation.
What is Absorbtion
400
This oral method provides prolonged drug delivery, targeted therapy and often improved bioavailability.
What is Buccal
400
This method of absorption requires energy; the molecules must move against the gradient.
What is Active Transport
400
This Lilly Neuroscience drug's half-life is 12 hours. It is slightly water soluble, not much of it will show up in the urine unchanged.
What is Cymbalta
400
The removal of a drug from plasma, clearance, as well as the distribution of a drug in various tissues throughout the body, Volume of Distribution, are important factors in determining ___ of a drug?
What is Half-Life
500
Can me measured either by blood level data, urinary flow, or by pharmacologic data.
What is Bioavailabilty
500
The mixture of active drug components and non-drug components.
What is Dosage Forms
500
This substance protects a drug as it moves through the stomach, so that it can reach the small intestine for absorption.
What is Enteric Coating
500
The recommended dosing for Cialis for Use as Needed, and Cialis for Daily use, respectively, for patients who have mild or moderate hepatic insufficiency.
What is Not to Exceed 10mg (PRN), QD dosing was not studied
500
There are 4 different types of drug metabolizer profiles: Extensive, Intermediate, poor and ______.