Malignant Hyperthermia
Dantrolene
ABC's of Managing MH 1
ABC's of Managing MH 2
WLSC Specific Information
100

Inhaled volatile gases and this depolarizing muscle relaxant can trigger a MH crisis.

What is Succinylcholine?

100

This is the only currently accepted specific treatment for MH.

What is Dantrolene?

100

Preoperatively we need to screen all our patients by asking them this question.

What is do you or your family have a history of MH or adverse anesthesia reactions?

100

This clinical sign can happen after the administration of succinylcholine.

What is Body Rigidity?

100

The MH cart is kept at this location.

What is across the hall from OR 1?

200

MH is usually inherited in an autosomal dominant pattern meaning children and siblings of a MH susceptible patient has this percentage of a chance of inheriting a MH gene deficiency.

What is 50%?

200

Dantrolene should only be diluted with this solution.

What is Sterile Water?

200

In the Emergency Treatment phase this is the first thing that will need to happen.

What is ASK for help and ASK for the MH cart and dantrolene?

200

Elevation of this is a clinical sign despite proper ventilation.

What is a rise in End Tidal CO2?

200

During a MH crisis besides personal in the building this entity is available for additional advice.

Who is MHAUS Hotline 1-800-644-9737?

300

Death can occur with a MH crisis secondary to this.

What is cardiovascular collapse?

300

You will need this many vials of Dantrolene and this many nurses to successfully treat a single patient.

What is 36 vials and 2-4 nurses?

300

This is the correct dose and way of administering Dantrolene.

What is 2.5 mg/kg given rapidly through a large bore IV?

300

Tachycardia, bradycardia, hypertension, hypotension and this can manifest as clinical signs of the circulatory system.

What are cardiac arrhythmias?

300

According to West Lakes Policy, the Anesthesia Team is responsible for direct diagnosis, treatment and this.

What is transferring the patient?

400

Signs of a MH crisis include an increased heart rate, greatly increased body metabolism, muscle rigidity, elevated body temperature and an increase of this in the blood.

What is acid content?

400

Sterile water should not be kept in this location.

What is in the refrigerator?

400

This electrolyte will need to be check during a MH crisis.

What is Potassium?

400

This needs to be monitored on all patients with procedures lasting over 30 mins and undergoing general anesthesia.

What is Body Temperature?

400

Cooling the patient is to be stopped if the patient’s core temperature reaches this.

What is <38*C?

500

These two anesthetic drugs are considered safe to give to a MH susceptible patient and are most commonly used at West Lakes Surgery Center.

What is Nitrous Oxide and Propofol?

500

In an episode of MH, muscle metabolism is dramatically increased secondary to an increase of calcium within the muscle. Dantrolene directly interferes with this to decrease calcium in the muscle cells.

What is muscle contraction?

500

If the patient is hyperkalemic, they can be treated with bicarbonate, calcium and these other two drugs.

What is Glucose and Insulin?

500

This clinical sign can be identified shortly after the patient has entered the OR.

What is Severe Masseter Spasm?

500

Cards have been added to the MH cart with this information.

What is the location of all supplies needed during a MH crisis?