Macronutrient Marvels
These provide concentrated energy and are vital for cell membrane integrity and transporting 4 specific vitamins.
What are fats / lipids?
Though not directly involved in wound healing, adequate levels of this vitamin are important for calcium absorption, which supports bone health in immobile patients
What is Vitamin D?
This trace mineral is essential for immune function, collagen formation, and cell proliferation
What is Zinc?
This percentage of the human body is comprised of water
What is approximately 55-60%?
Adult male ~60%, adult female ~55%, children 65%, infant 75%. Can vary according to fat mass (lean tissue holds more water).
This term refers to the breakdown of skin and tissue due to prolonged pressure, friction, or shear
What is a Pressure Injury/Ulcer?
This amino acid plays a key role in collagen formation, immune function, and acts as a precursor for nitric oxide which improves circulation and oxygen delivery to the tissues.
What is Arginine?
This water-soluble antioxidant is essential for collagen synthesis and immune function.
What is Vitamin C?
A deficiency in this mineral can impair oxygen delivery to the wound
What is Iron?
Dehydration can lead to decreased tissue perfusion and impaired nutrient delivery to the wound, potentially causing this issue
What is Delayed healing/tissue breakdown?
A provider reaches out with concern that a patient's prealbumin level has significantly decreased, despite you knowing that the patient is having adequate protein intake and good wound healing. What other lab value would you recommend checking to help explain this unexpected drop?
What is C-reactive protein (CRP) or another inflammatory marker?
This ingredient in Juven, a metabolite of the amino acid leucine, is particularly noted for its role in preventing muscle protein breakdown and enhancing protein synthesis, which is crucial for maintaining lean body mass during wound healing.
What is hydroxymethylbutyrate or HMB?
This fat-soluble vitamin has the unique ability to reverse the inhibitory effects of anti-inflammatory steroids on wound healing. Crucial for epithelialization, cellular differentiation, and immune function, this vitamin is found in carrots, sweet potatoes and leafy greens.
What is Vitamin A?
These electrolytes are critical for fluid balance and nerve and muscle function, both vital for overall healing.
What are Potassium and Sodium?
This type of beverage can improve hydration better than plain water by also providing some electrolytes
(hint: medical term/acronym)
What is Oral Rehydration Solution?
In addition to its key amino acids, Juven provides this specific type of hydrolyzed protein, rich in glycine and proline.
What are collagen peptides?
This specific amino acid supports cell production and tissue regeneration to help with the formation of new skin. You might see it be supplemented in the burn population.
What is Glutamine?
This antioxidant vitamin protects cell membranes from oxidative damage during inflammation, and can be found in nuts, seeds, and oils.
What is Vitamin E?
While its primary role is bone health, this mineral also plays a role in cellular signaling during wound repair
What is Calcium?
This is a physical sign of dehydration
What is Poor skin turgor / dry mucous membranes?
This lifestyle factor, often linked to poor circulation and impaired oxygen delivery, negatively impacts wound healing
What is Smoking?
This diagnosis impairs immune response, which can delay wound healing.
What is Protein-calorie malnutrition?
This group of vitamins is involved in metabolic pathways that produce energy, which is crucial for cell proliferation and repair during the wound healing process. Two specific vitamins in this group are critical for DNA synthesis and cell division which are necessary to regenerate new tissue.
What are B vitamins?
DNA synthesis: folic acid and vitamin B12
This mineral, found in whole grains and nuts, is a cofactor for many enzymes involved in energy production and protein synthesis
What is Magnesium?
Explain how fever in a patient with a wound can significantly increase their fluid requirements.
What is because fever increases metabolic rate and insensible fluid losses through sweating and respiration, requiring additional fluid intake to compensate?
This phase of wound healing involves the formation of new tissue and blood vessels, often characterized by a beefy red appearance
What is the Proliferative/Granulation phase?