DNA Replication
Cell Division
Chromatin
Nucleic Acids
Potpourri
100

The enzyme seals nicks in the phosphodiesterase backbone.

What is ligase?

100

This protein is responsible for the X shape of chromosomes because it holds sister chromatids together.

What is cohesin?

100
The action of these proteins move DNA to a more heterochromatic state.

What are HDAC and methyl transferase?

100

70% of the DNA bases in a cell are adenine, so by Chargaff's rule, guanine would be present in this relative percentage.

What is 30%?

100

Nitrogenous bases are linked by this type of bond.

What are H-bonds?

200

The helicase is on the lagging strand in these organisms.

What are prokaryotes?

200

A pair of homologous chromosomes has this many telomeres after S phase.

What is 8?

200

The interaction of this histone protein forms the 30 nm fiber.

What is H1?

200

70% of the RNA bases in a cell are cytosine, so by Chargaff's rule, thymine would be present in this relative percentage.

What is 0%?

200

This structural feature confers greater specificity, allowing tighter binding when the DNA has a particular sequence.

What is the major groove?

300

This protein prevents secondary structures from forming on the lagging strand.

What are SSBs?

300

A organism has 6 pairs of homologous chromosomes at G1 phase, it would have this many sister chromatids at the start of mitosis.

What is 24?

300

Acetylation can occur on this amino acid. Provide the 1-letter code.

What is K?
300

Of the strands CTGAGCA (Strand 1) and ATGTCTA (Strand 2), this strand has a higher relative melting temperature. 

What is Strand 1?

300

What word classifies the type of bonds that are formed between the sugar and phosphate backbone?

What is covalent?
400

This protein uses energy to relieve superhelical strain on sister chromatids prior to mitosis.

What is topoisomerase 2?
400

This type of microtubule is anchored at the centrosome and has its plus end at the cell cortex. Involved in Anaphase B, this MT relies on the retrograde motion of dynein.

What are astral microtubules?

400

Heterochromatic regions near telomeres are described by this adjective.

What is constitutive?

400

The sequence of an RNA strand is CGAAAC. Provide the beginning 3-bp sequence that will form a hairpin loop structure with this sequence. sequence.

What is GUU?

400

What mechanism underlies how chromatin remodeling complexes move?

What is ATP hydrolysis?
500

Draw a bidirectional replication fork.

What is look at Zoe's slides? :)

500

A diploid animal cell has 10 pairs of homologous chromosomes in interphase, and thus has this many sister chromatids in G1 phase.

What is 0?

500

The ABC1 gene is normally highly expressed. You discover abnormal cells in which the ABC1 gene is expressed at a very low level. What type of protein might be inactive in the abnormal cells?

What is HAT or demethylase?

500

The inverse complement of this DNA strand is GTTGC.

What is GCAAC?

500

This strand is the template for lagging strand replication; think in terms of telomeres.

What is the 3' overhang strand?