Multiple Myeloma
Hodgkin's Lymphoma
Non-Hodgkin's Lymphoma
100

This acronym summarizes the classic end-organ damage used to diagnose symptomatic multiple myeloma.

What is CRAB?

100

The characteristic malignant cell of Classical Hodgkin Lymphoma.

What is a Reed-Sternberg cell?

100

The "R" in R-CHOP stands for this monoclonal antibody.

What is Rituximab?

200

A patient has:

  • Calcium 12.2 mg/dL
  • Hemoglobin 8.4 g/dL
  • Creatinine 2.1 mg/dL
  • Peripheral Neuropathy

How many CRAB criteria are present?

What is 3?

(Hypercalcemia, Anemia, Renal Impairment)

200

A patient presents with:

  • Fever
  • Drenching night sweats
  • Unintentional weight loss

What are these collectively known as?

What are B symptoms?

200

A patient with DLBCL is receiving rituximab. Which viral infection should always be screened for before treatment begins?

What is Hepatitis B?

300

A patient receiving Dara-VRd develops burning feet, numbness, and difficulty buttoning a shirt. Which medication is the most likely cause?

What is Bortezomib?

300

A patient receiving ABVD develops a persistent dry cough and worsening shortness of breath. Which medication should be suspected first?

What is Bleomycin?

300

A patient receiving R-CHOP develops numbness in the fingertips, difficulty buttoning clothing, and mild balance problems. Which medication is the likely culprit?

What is Vincristine?

400

A patient with multiple myeloma and poorly controlled diabetes develops fasting blood sugars of 280 mg/dL after starting treatment. Which medication is most likely responsible?

What is Dexamethasone?

400

A 70-year-old patient with severe COPD is diagnosed with Stage IV Hodgkin Lymphoma. Which component of ABVD would cause the greatest concern?

What is Bleomycin?

400

A patient receiving R-CHOP has:

  • Resolution of B symptoms
  • No new lesions on PET
  • Deauville score of 2

How would you interpret this treatment response?

What is an excellent response (PET-negative response)?

500

A patient with:

  • β2-microglobulin 7.0 mg/L
  • Elevated LDH
  • del(17p)

would be classified as which Revised International Staging System stage?

What is R-ISS Stage III?

500

A patient receiving BV-AVD develops numbness and tingling that interferes with walking and activities of daily living. Which medication is most likely responsible?

What is Brentuximab Vedotin?

500

Two patients are diagnosed with lymphoma. Patient A has follicular lymphoma and is placed on observation. Patient B has DLBCL and begins R-CHOP immediately. What key difference between these diseases explains the different treatment approaches?

What is DLBCL is an aggressive lymphoma requiring prompt treatment, whereas follicular lymphoma is typically an indolent lymphoma that may be observed initially?