BCL-2 Family of proteins are regulators of the intrinsic pathway of apoptosis
What are the two pore-forming pro-apoptotic proteins in the BCL-2 family?
BAK and BAX
What is the name of the ballet that Alexis Truta performed as the lead dancer?
Sleeping Beauty
In 1990-1994, what undergraduate university did Dr. James L. LaBelle, MD PhD attend?
Lawrence University
B cells and T cells are a part of the _____ immune system.
Adaptive
How many people in LaBelle Lab are dog owners (family dogs included)?
4 (James, Jocelyn, Ryan, Viren)
What three anti-apoptotic proteins does BH3 mimetic Navitoclax directly target and inhibit?
BCL-2, BCL-XL, BCL-W
What is Elaine Lee and Trang Nguyen's star sign?
Virgo
What is James' middle name?
Lawrence
Name at least two types of antigen presenting cells.
Dendritic cells, macrophages, and B cells
How many Pokemon cards has Trang collected on Pokemon Trading Card Game Pocket mobile game?
4,427 cards
According to James, which is correct?
A) BCLxL
B) Bcl-xl
C) BCL-XL
D) BCL-XL
E) Bcl-xL
D) BCL-XL
What color belt is Jocelyn Hsu in Taekwondo?
Red with black stripe
What is James favorite genre of music?
Opera
Which MHC class is recognized by helper T cells (CD4+)?
MHC class II
What is Zachary Yasinov favorite swimming stroke?
Sprint freestyle
Which lab member is a part-time politician?
Joshua Ho, TN state policy representative for the TN Academy of Nutrition & Dietetics
True or False: During normal secondary immune response, more IgM antibodies are produced than IgG antibody.
False. While IgM antibodies are the first to be produced in a primary response, memory B cells generated during the primary response produce more IgG antibodies during secondary antigen exposure.
Which lab member graduated from the birthplace of Gatorade?
Rebecca Abraham
Ed owns a very cute cat. What is it's name?
Puff
What was James nickname that was given to him during his cross-country trucking trip adventure as a child?
French Fry
Th17 cells are most crucial for defense against which type of organism?
A) Parasitic helminths
B) Intracellular bacteria
C) Extracellular fungi
D) Viruses
C) Extracellular fungi
Th17 cells are primarily involved in the defense against extracellular bacteria and fungi.