Routes and Administrations
Medication safety and adverse effects
Pharm kinetics and dynamics
Drug interactions and effects
Regulation and FDA Guidelines
100

Which route of administration has the fastest absorption rate?

What is intravenous (IV)

100

Why are Tall Man Letters used in medication names?

What is to reduce medication errors by distinguishing look-alike, sound-alike drugs

100

Which organ is primarily responsible for drug metabolism?

What is the liver

100

Which beverage should be avoided with CYP450-metabolized drugs?

What is grapefruit juice

100

 What does the FDA Pregnancy and Lactation Labeling Rule (PLLR) replace?

What is the old A, B, C, D, X pregnancy risk categories

200

Why should enteric-coated aspirin not be crushed?

What is to prevent stomach irritation

200

A nurse prepares an IV penicillin infusion. The patient reports itching, dizziness, and shortness of breath. What should the nurse do first?

What is stop the infusion immediately and assess for anaphylaxis

200

What is the primary organ responsible for drug excretion?

What is the kidney

200

Why are warfarin and heparin given together for a short time in anticoagulation therapy?

What is because warfarin takes several days to reach therapeutic levels

200

What classification of drugs have the highest potential for abuse?

What is Schedule I

300

What is the primary reason why alendronate (Fosamax) must be taken before breakfast?

What is to maximize absorption

300

Which sources are considered reliable for medication safety? (Select all that apply)

  • A) Websites ending in .com
  • B) Published journals
  • C) Pharmacists
  • D) Physicians' Desk Reference
  • E) Pharmaceutical sales representatives

What are B, C, and D

300

What is the term for the lowest concentration of a drug in the bloodstream before the next dose?

What is the trough level

300

What is an adverse drug reaction, and how is it different from a side effect?

What is an unintended harmful reaction, while a side effect is expected but manageable?

300

What does the Institute for Safe Medication Practices (ISMP) recommend to prevent medication errors?

What is the use of Tall Man Letters

400

A patient is prescribed sublingual nitroglycerin for chest pain. How should it be taken?

What is placing it under the tongue to dissolve and absorb into the bloodstream quickly

400

A patient refuses to take their prescribed medication. What is the correct nursing action?

What is document the refusal and notify the provider

400

What is the difference between an agonist and an antagonist

What is an agonist activates a receptor, while an antagonist blocks it  

400

 A patient taking opioids long-term develops feels anxious and irritable after suddenly stopping. What is this called?

psychological dependence

400

What is a black box warning, and why is it important?

What is an FDA-mandated warning for serious or life-threatening drug risks?

500

What is the first-pass effect, and which route bypasses it

What is liver metabolism before systemic circulation, and the IV route bypasses it

500

 A patient develops severe pain when drug is withheld

What is physiological dependence

500

Why should patients on warfarin avoid eating excessive amounts of leafy greens

What is because vitamin K can interfere with warfarin’s anticoagulant effects

500

What is the difference between therapeutic classification and pharmacologic classification?

What is therapeutic classification groups drugs by treatment use, while pharmacologic classification is based on mechanism of actio

500

A pharmaceutical company claims their new drug does not need FDA approval. What is the correct response?

What is all drugs in the U.S. must be FDA-approved before being marketed

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