An arm and a leg
developing...developing.. Developed!
No conflicts of interest
Big Boy
Physiolo-goaway
100

What is likely to be damaged if the surgical neck of the humerus is fractured?

posterior humeral circumflex a and axillary nerve (C5,C6)

100

Growth along the anterior posterior axis causes…what regulates it? 

Growth along the dorsal ventral axis causes…what regulates it?

Thumbs different from fingers and great toe different from pinkie toe, SHH regulation

Palm distinct from dorsum of hand, sole of foot from top of foot, WNT7a regulation

100

What weight bareing mobility aid provides the most relief?

  • Crutches
  • Walker
  • Hemiwalker
  • Rollator

what is ... 

crutches

100

81. What muscle fibers fatigue the quickest and which have myoglobin content?

Type I – red myoglobin – oxidative – require oxygen, will be highly vascularized

Type IIa – red myoglobin - oxidative – require oxygen, will be highly vascularized

Type IIb/x – fatige the fastest – glycolytic – do not require O2, less vascularized, won’t need myoglobin (as much)

100

51. How does myelin enhance conduction of an action potential? include membrane resistance, capacitance, time constant, and length constant.

what is...

Increases membrane resistance which increases the length constant so the impulse can travel farther

Mylin decreases capacitance which will decrease the time constant and allow the wave to move faster

200

Where does the radial nerve travel?


BE SPECIFIC

what in the world is...

the radial groove of the humerus

200

too much ZPA signals will…

Increase AER  long limbs and polydactyly

200

90. What are the most important things to consider when selecting the right mobility aid?

  • What is 
  • Postural stability
  • Muscular weakness
  • Coordination
  • Drip of the aid
200

31. What part of the muscle detects stretch?

what is 

Intrafusal fibers – special contractile fibers within a muscle spindle

200

62. What is the main source of ROS in the body? What are some other sources?

The mitochondrial ETC – main source

NADPH oxidase – superoxide from NADPH and O2

Metabolic byproducts

Ionizing radiation, reactive metals

300

What are the borders of the popliteal fossa?

What are the contents of the popliteal fossa?

what is ...

Biceps femoris

gastrocnemius medial and lateral heads

semimembranosus


what is ...

Medial  lateral

Popliteal a, v, tibial n

300

you are a zygote on 4th maybe 5th day of gestation, floating through the uterus. You think, ah, what a wonderful day out, plenty of sites to implant. I'm am not sure I want to implant yet, but I know I want to be good embryo. I don't want to implant too low and cause...

placenta previa - where the placenta cover's the cervix, blocking the baby's exit. 

300

72. A deontologist would say, which of the following?

  • Focus on the means rather than the ends
  • Focus on the ends
  • Focus on the process
  • Just focus

what is... 

Focus on the means (action motive) rather than the ends (consequences) – absolutism

300

Glycogen synthase is active when it is … glycogen phosphorylase is active when it is …

dephosphorylated, phosphorylated

300

99. Phosphorylation of PFK2 and FBPase2 will (multiple right answers)

A. Increase F26BP production

B. Increase PFK1 activity

C. Increase FBPase 2 activity

D. Increase F6P in the cell


Answers C and D


phopsphorylation of PFK2  PFK2 activity decreases. Therefore, FBPase 2 activity will increase  increase F6P  inhibiting progression through glycolysis

400

C5, C6, C7, C8, T1 dermatomes supply what?

  • C5 – lateral upper limb
  • C6 – Thumb
  • C7 – Index and middle fingers
  • C8 – little finger
  • T1 – medial upper limb
400

The posterior divison of the brachial plexus is from the ___ border or ____ condensation and forms ____ and _____. 

Posterior division – extensors and supinators – from post-axial border, posterior condensation

400

If the outcome criteria is not objective or unbiased, what bias is likely to occur?

Selection bias – representative cohort or not

Susceptibility bias – classify patients correctly or not

Detection bias – objective criteria and unbiased or not – answer

400

Why does temporal summation (in muscles) result in a greater tension for longer time?

Calcium has not fully sequestered back into the sarcoplasmic reticulum, therefore, when the next stimulus comes, more Ca2+ is released in addition to the Ca2+ already in the sarcoplasm  greater contraction, greater tension

400

103. Glyogenin 1 is a result of … and results in …

what is ...

Deficiency in glycogenin leading to exercise intolerance because cannot make glyocen stores

500

what nerves supply each of the following? Include spinal roots! Denote which is related to winged scapular matey. 

brachioradialis muscle

lumbricals 3 and 4 muscle

superior gemellus muscle

serratus anterior muscle

subscapularis muscle

brachioradialis - radial n C567

lumbricals 3 and 4 - deep branch of the ulnar n C8T1

superior gemellus muscle - nerve to obturator internus L5S1S2

serratus anterior - long thoracic n C567

Subscapularis - subscapular n C56

500

24. Disruption of FGF8 signaling will result in

Inability to maintain the AER

Ceasing of further limb growth and development

500

If there is a dropout in a study, it indicates that the outcomes are…known or unknown?

Known – dropouts means we recorded drop outs, we know the outcomes

Unknown – this is when we lose subjects, and do know/cannot contact them

500

PRANKED! Ethics Question not muscle metabolism question

In distributive justice, what are the two principles that arise?

Equal right to basic liberties

Social and economic inequalities based on greatest benefit to least advantaged, and fair equality of opportunity

500

104. Decreased Carnitine pamitoyltransferase II leads to...

what is...

Carnitine and acylcarnitine build up and stop. The acylcarntitine cannot be broken down because CPTII is defective. As a result, carnitine in the matrix cannot be pushed out because the carnitine acytlcarnitine translocase relies on antiport to transport each in/out of the matrix. Inabiltiy to free acetyl CoA from acylcarnitine  inability to carry out B oxidation. Can only rely on glycogen stores and glucose for energy



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