the primary goal of acid-base homeostasis


Maintain a normal pH
the most significant volatile acid

what is:
Carbonic acid H2CO3
the primary event that leads to a High CO2 and tries to compensate through high HCO-3 which takes place slowly is called
Ph(H+ -hydrogen ion) range: 7.35-7.45
acid <-------7.40------->alkaline(base)
PaCO2 range: 35-35mmHg
akaline<----------40-------->acid
HCO-3 range: 22-26Eg/L
acid<-----------24----------->alkaline
EX: Ph 7.30/PaCO2 50/ HCO-3 30
ph- acid/PaCO2 acid/ HCO-3 alka
what is:
Respiratory acidosis
-Increasing alveoli ventilation will fix this

the organ system that excretes H+ from the body

what is the:
Kidneys
the two points would you use to calibrate an O2 analyzer

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what is set at:
21% & 100%
the following are indications for ____
-need to evaluate ventilation(PaO2), acid-base balance(pH & PaCO2), oxygenation status(PaO2 & SaO2) oxygen- carrying capacity of blood(PaO2,HbO2, total Hb, dyshemoglobins)
-to assess the patient's response to therapy or diagnostic test
-monitor severity & progression of documented disease process
-sudden, unexplained dyspnea, acute shortness of breath/tachypnea, cyanosis
-heavy uses of accessory muscles(WOB)
-changes in ventilation settings
-CPR
what is an:
ABG(arterial blood gas)
The driving force behind Bicarbonate buffers is the process of ____

what is: ventilation
the ratio for HCO3- dissolving CO2(this will give you a normal pH balance)
what is:
20:1
the two mechanisms responsible for maintaining a stable pH

what is:
Isohydric buffering
Pulmonary ventilation
the primary chemical event caused by low CO2 levels that could be compensated through low HCO-3 (takes place slowly)
Ph(H+ -hydrogen ion) range: 7.35-7.45
acid <-------7.40------->alkaline(base)
PaCO2 range: 35-35mmHg
akaline<----------40-------->acid
HCO-3 range: 22-26Eg/L
acid<-----------24----------->alkaline
EX: ph 7.60/PCO2 30/HCO-3 20
ph alk/PCO2 alk/HCO-3 acid
what is:
Respiratory alkalosis

the ___ device is an electrochemical O2 analyzer that slowly measures PO2, not FiO2 concentration, using a gold anode and a lead cathode to generate a chemical reaction that creates current flow across the pole with no external battier source required, but often needs the fuel cell replaced.

what is a:
Galvanic Fuel cell
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the 3 values that are measured on the blood gas analyzer


what is measured:
pH, pCO2, p02
when do you do an Allen's test?
what is:
before radial artery puncture ONLY
What is the most important & abundant Non-Bicarbonate Buffer in a closed system?
what is:
Hb

the ratio indication of pH level needed for HCO-3 to dissolve CO2, causing the result to be alkalosis

what is:
> 20:1
the term that matches the following statement:
-the solution that resists large changes in pH upon the addition of an acid or a base
what is a:
Buffer solution
the primary chemical event that is caused by low HCO-3 levels and could be compensate through low CO2(hyperventilation)(works fast)
Ph(H+ -hydrogen ion) range: 7.35-7.45
acid <-------7.40------->alkaline(base)
PaCO2 range: 35-35mmHg
akaline<----------40-------->acid
HCO-3 range: 22-26Eg/L
acid<-----------24----------->alkaline
EX: Ph 7.05/PCO2 20/HCO-3 8
ph acid/PCO2 alk/HCO-3 acid
what is:
Metabolic acidosis

the _____ device that measures FiO2 then uses O2 to produce a reduction-oxidation reaction, by O2 molecules diffusing through the sensor membrane into the electrolyte and polarizing voltage fastly with electricity.
-made of platinum cathode & a silver-silver chloride

what is a:
Clark electrode(polarographic)

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the 3 values that are calculated on the blood gas analyzer


what is:
Calculated HCO3-, BE(base excess), Hb
What should you do when doing an arterial blood gas and the pulsatile blood flow stops?
what is:
you should slowly withdraw
the bicarbonate buffer uses the aid of ____ and is then converted to ____, which is excreted during exhalation.


what is:
H2CO3
CO2
the ratio indication of pH level needed for HCO-3 to dissolve CO2, giving an acidosis result


what is:
<20:1
The bicarbonate buffer system for _____ acids takes H+(hydrogen ion) to be buffered by HCO3(bicarbonate ions) and converts it to CO2 and H2O. The CO2 formed is then eliminated in exhaled gas.


what is:
Fixed acids
the primary chemical event that is caused by high HCO-3 levels and could be compensated through high CO2 level(Hypoventilation)(place fast)
Ph(H+ -hydrogen ion) range: 7.35-7.45
acid <-------7.40------->alkaline(base)
PaCO2 range: 35-35mmHg
akaline<----------40-------->acid
HCO-3 range: 22-26Eg/L
acid<-----------24----------->alkaline
EX: Ph 7.49/PCO2 60/HCO-3 40
Ph alk/PCO2 acid/alk
what is:
Metabolic alkalosis

side note: when both respiratory & kidney are experiencing this simultaneously that is a mixed/ combined result
the _____ electrode measures CO2 through sodium bicarbonate, which reacts with the CO2; The reaction changes the pH in the electrode, which corresponds to a change in potential difference, and this is measured. The CO2 is then inferred from the change in pH.

what is: severinghaus

the prevention of the following; air getting into a sample and needle stick injuries is the purpose of ____

what is:
needle capping devices
If a patient was stress hypoventilating during an ABG, what may the results conclude?
what is:
Respiratory Alkalosis
-let the lab know
_____ increases the CO2 removal, causing non-bicarbonate buffers to release H+

what is:
Hyperventilation
-acidosis activates CNS receptors, signaling the need to increase VE(blames kidneys)
the normal arterial blood gas range for pH

what is:
pH 7.35 to 7.45

the NON-BICARBONATE closed system takes on the role of buffering when there is no gas to remove acid by ventilation, so H+(Hydrogen ions) bind with phosphates, proteins, and Hb by H2CO3(carbonic acid) donation. The ____ acids are excreted through this process. The source responsible is tissue metabolism producing massive amounts of CO2, which is then hydrolyzed(water molecule added).
-NB can eliminate fixed acids


what is:
volatile acids
-equilibrium with dissolved gas.
-The only one of physiologic significance in the body is carbonic acid(H2CO3-)
the effect H+ has on pH
-Higher H+ concentration: The pH is lower, and the solution is more acidic.
-Lower H+ concentration: The pH is higher, and the solution is more basic

what is: an
inverse relationship
the causes of RT needing to pick an alternative site for an ABG, which of the following would be the reasons:
-Failed Allen's test
-Peripheral vascular disease or infection
-Surgical Shunt
-anticoagulation therapy
Causes: Failed Allen's test, Peripheral vascular disease or infection, Surgical Shunt
NOT a cause- ANTICOAGULATION THERAPY IS NOT A REASON TO CHOOSE A NEW SITE
the cause of a false high on a pulse oximeter

what is: Carboxyhemoglobin (COHb)
the source of arterial blood follow?
what is:
the lungs. An ABG sample tells how well they are working at oxygenating the blood.
the _____ organ system that is the immediate defense against the accumulation of H+ works fast to remove volatile acids
what is the:
lungs
the normal arterial blood gas PaCO2

what is:
PaCO2 35-45mmHg
the open bicarbonate system process is H2CO3 hydrolyzed to CO2. What two components does this system consist of?

The following occurs from them:
-(primary for fixed acids only) is composed of H2CO3 and HCO-3
-uses continuous ventilation to remove CO2
-Carbonic acid is converted to CO2 and removed
what is:
Plasma (35%)
Erythrocyte(18%)

the _____ monitoring gives accurate data by doing an ABG to establish a precise baseline of info. It can cause a greater risk of arteriospasm, air clot or blood emboli, infection, hematoma, hemorrhage, anaphylaxis(anesthetic), pain, decrease in BP & HR(Vasovagal response), trauma to the blood vessel, and arterial occlusion.
-insertion of a device

what is:
invasive
the risks of complications of drawing an ABG are

what is:
Arteriospasm-an involuntary contraction of an artery. It can be caused by manipulation or fresh blood around an artery and can last from minutes to days.
Embolization-stop blood flow to a specific blood vessel
Infection
Hemorrhage -an acute loss of blood from a damaged blood vessel
the ABG sample errors(Preanalytical)
-Decrease in CO2, Increase pH, O2 toward 150mmHG
-CO2 46, O2 40, pH normal low
-Improper cooling, increased CO2, decreased O2 & pH

if you have no recapping device use the single-handed _____ method
what is the:
scoop method
the _____ organ system buffers slowly & thoroughly to remove fixed acids

what is:
the kidneys

the normal arterial blood gas range for PaO2

tip: the grade range you want:)
what is:
PaO2 80-100mmHg
the _____ system uses carbonic acid that is converted to CO2 and removed with a Bicarbonate buffer.

what is:
an open system
the ____ monitoring is an RT's first choice which uses pulse ox, EKG, and heart monitor leads and gives real-time tending to produce ongoing results.


what is:
non-invasive
(just put on skin not under like invasive)

the ____ test that shows collateral circulation when doing a radial ABG to indicate collateral circulation.

what is an:
Allen's test

the hypoxemia normal(range should be 80-100 mmHg)
Mild
Moderate
Severe
what is:
mild: 60-79 mmHg
moderate: 59-40 mmHg
severe <40mmHg
the capnometry measures ___ levels
CO2 (respiratory gases)
_____-_____ allows validation of the reported values on a blood gas report that gives pH, PCO2, HCO-3


what is the
Henderson-Hasselbach
the normal arterial blood gas range for HCO-3

what is:
HCO-3 22-26mEq
the ______system that uses Hb, inorganic & organic phosphates, and plasma proteins to donate a hydrogen ion (H+) and combine with hyperventilation for secretion.
-all components remain in the system
what is a:
closed system
The 3 sites available for drawing an ABG

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what is the: radial, femoral, brachial

the Allen's test steps in order
1. occlude both radial & ulnar artery
2. have the patient make a fist and open
3. Release the ulnar artery
Blanched hand pinks up in 1-2 seconds if greater than 10 seconds is considered a fail, and another site should be chosen
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the following are reasons to use _____ site during ABG(most common)
-is near the surface and easy to stabilize
-collateral circulation usually exists(confirmed with the Allen test)
-No large veins are near
what is the:
radial artery
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two ways the body keeps the blood pH constant regardless of how much CO2 is produced
(maintains normal pH even in the face of massive CO2 production)


what is:
Isohydric buffering
Ventilation
Hypoxemia, Hyperventilation, anxiety, fever, pain, stimulants, drugs, and mechanical ventilation are all causes of ____
what is:
Respiratory alkalosis