A patient taking gentamicin should be monitored for which toxicities?
Ototoxicity and nephrotoxicity
What is the MOA of acyclovir?
Inhibits viral DNA synthesis
What is a serious cardiac side effect of fluconazole?
QT prolongation and torsades de pointes
What is the primary risk of aspirin in children with viral infections?
Reye’s syndrome
A patient taking tetracycline is prescribed calcium supplements. What is the priority?
Hold calcium; it interferes with tetracycline absorption
Which class of antibiotics can cause Achilles tendon rupture?
Fluoroquinolones
Which antiviral is used for Influenza A prophylaxis and can cause seizures?
Rimantadine
What nursing teaching is essential for clotrimazole use?
Do not use in systemic candidiasis; monitor liver function
Which anti-inflammatory has no significant GI toxicity?
Acetaminophen
A patient on sulfonamides develops a widespread skin rash. What should the nurse do?
Stop the medication and notify the provider—possible Stevens-Johnson Syndrome
Which antibiotic class is contraindicated with calcium and causes teeth staining?
Tetracyclines
Which antiviral requires cautious use in renal impairment and can cause phlebitis?
Acyclovir
Which antifungal can cause Stevens-Johnson Syndrome and hepatotoxicity?
Fluconazole
Which NSAID can cause fluid retention and increased risk of MI?
Ibuprofen
A nurse is administering vancomycin. What is the best action to prevent adverse effects?
Infuse over at least 60 minutes
A nurse is educating a patient on sulfonamides. Which teaching is correct?
Drink 2L of water daily to prevent kidney stones
What should a nurse monitor in a patient taking oseltamivir?
Seizures and renal function
Fluconazole is contraindicated with which types of medications?
QT-prolonging drugs like erythromycin and quinidine
A patient on ketorolac complains of black stools. What should the nurse suspect?
GI bleeding
A patient reports dark urine and fatigue after starting metronidazole. What should the nurse do?
Evaluate for hepatotoxicity
Vancomycin must be infused slowly to prevent which reaction?
Red man syndrome
Which antiviral requires dose adjustments based on weight in obese patients?
Acyclovir
What are common GI effects of antifungals?
Nausea, vomiting, elevated LFTs
What lab should be closely monitored for a patient on high-dose acetaminophen?
Liver function tests (AST/ALT)
A patient prescribed oseltamivir has had flu symptoms for 3 days. What is the nurse’s best action?
Withhold the drug; it's effective only within 48 hours of symptom onset