DNA to RNA
Translation & Ribosomes
Gene Regulation
Mutations & Epigenetics
Molecular Tools
100

This enzyme reads the DNA template strand and synthesizes mRNA during transcription.



What is RNA polymerase?



100

The ribosome subunits are composed of rRNA and these molecules.



What are proteins (ribosomal proteins)?



100

In the lac operon, RNA polymerase binds here to begin transcription.




What is the promoter?


100

A mutation that changes one nucleotide but does NOT change the amino acid is called this.



What is a silent mutation?




100

The central dogma of molecular biology describes the flow of information in this order.



What is DNA → RNA → Protein?



200

This enzyme is responsible for building the mRNA strand during transcription.



What is RNA polymerase?



200

This type of RNA brings amino acids to the ribosome during translation.



What is tRNA?



200

When lactose is absent, this molecule blocks transcription of the lac operon by binding to the operator.



What is the repressor protein?



200

This type of mutation inserts or deletes a nucleotide, shifting the entire reading frame.



What is a frameshift mutation?



200

The three components of a nucleotide.



What are a phosphate group, a sugar (deoxyribose or ribose), and a nitrogenous base?



300

The strand of DNA that RNA polymerase reads is called this.


What is the template strand?



300

The mRNA codon AUG codes for this amino acid and also serves as the start codon.



What is methionine?



300

Gene expression is turned ON in the lac operon when this sugar is present.



What is lactose?



300

A point mutation that changes one amino acid to a different one is called this.



What is a missense mutation?



300

This term describes the fact that multiple codons can code for the same amino acid.



What is the genetic code being redundant (or degenerate)?



400

In eukaryotes, non-coding sections of pre-mRNA that are cut out before translation.



What are introns?



400

Translation ends when the ribosome reaches one of these on the mRNA.



What is a stop codon (UAA, UAG, or UGA)?



400

In eukaryotes, transcription factors and RNA polymerase bind to this region upstream of a gene.



What is the promoter?



400

UV radiation can cause these two thymine bases to bond together, distorting DNA.



What are thymine dimers?



400

A section of DNA that codes for a protein is called this.



What is a gene?



500

mRNA is modified before leaving the nucleus by adding a 5' cap and this tail.



What is a poly-A tail?



500

Each three-nucleotide sequence on mRNA that codes for an amino acid is called this.



What is a codon?



500

These DNA sequences far from a gene can still increase transcription by looping toward the promoter.



What are enhancers?



500

A mutation that creates a premature stop codon, cutting the protein short.



What is a nonsense mutation?



500

This process uses mRNA as a template to build a protein, reading it 5' to 3'.



What is translation?



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