Hemoglobin and Oxygen Transport
Iron Homeostasis
Disorders of RBC production
RBC Metabolism and Anemia
Intro to Blood and Hematapoiesis
100

The number of globins in a hemoglobin 

What is 4?

100

A protein inside cells that stores iron 

What is ferritin?

100

The term for a low platelet count 

What is thrombocytopenia?

100

RBCS make ATP using anaerobic glycolysis because they lack this cell organelle 

What are mitochondria?

100

T lineage cells mature in this organ 

What is the thymus?

200

The most common type of hemoglobin found in adults

What is HbA?

200

Cells display these receptors when they need more iron 

What are TfR1 receptors?

200

All blood cells are derived from this type of stem cell 

What are hematopoietic stem cells?

200

IV Iron is combined with this compound in order to prevent toxicity 

What is sugar (carbohydrates)?

200

The type of stain used to visualize hematopoietic cells in smears 

What is a Wright stain?

300

Oxygen binds to hemoglobin when it is in this state 

What is a "relaxed" state?

300

The oxidation state of iron that allows for better storage 

What is Fe3+?

300

Since 1998, grain products in North America have been fortified with this compound to help prevent a type of anemia 

What is folate (folic acid)?

300

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What is G6PD (glucose-6-phosphate-dehydrogenase)?

300

This factor may stimulate the self-renewal of hematopoietic stem cells (HSCs) 

What is stem cell factor (SCF)?

400

A majority of carbon dioxide in the blood is transported as this ion

What are bicarbonate?

400

Tissues with high oxygen demand will have a monomer of hemoglobin called this 

What is myoglobin?

400

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What is hookworm infection?

400

Folate deficiency leads to deficient synthesis of this compound, leading to deficient DNA replication 

What is dTTP (Deoxythymidine triphosphate)?

400

The precursor cell that form platelets through budding of the cytoplasm 

What are megakaryocytes?

500
These four factors cause P50 to shift to the right, favoring unloading in tissues 

Short term: Temperature, pH, CO

Long-term: 2,3-BPG 

500

The inheritance pattern for hereditary HFE hemochromatosis

What is autosomal recessive?

500

A group of symptoms that is unique to B12 (Cobalamin) deficiency

What are neuropsychiatric symptoms?

500

Plasma or serum levels of this enzyme provide a good measure of necrotic cell death 

What is Lactate Dehydrogense (LDH)?

500

This cytokine controls the maturation of monoblasts 

What is M-CSF (Monocyte Colony-Stimulating Factor)? 

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