Immunostains
Immunostain used to confirm lung primary
TTF-1
A milky appearance in the presence of an otherwise fine stain quality would suggest what preparatory issue?
Water in xylene
The strain of HPV most commonly associated with endocervical adenocarcinoma is...
HPV 18
Multiple nodules occurring is more common in primary disease or metastatic disease?
Metastatic
What is the most common type of fire extinguisher found in the lab?
ABC
Neuroendocrine
The alcohol steps used in the pap stain process are for what purpose?
Allow transparency through cells
Air-drying
Compared to other types of lung cancer, this type tends to occur more peripherally within the lung.
Adenocarcinoma
What is the most effective universal precaution to take in the lab to prevent the spread of infection and contamination?
Hand washing
or
PPE
A positive result for this immunostain is diagnostic of a GIST
DOG-1
What is the purpose of xylene in the staining setup?
Clearing agent
Patient is a 29 y.o. female. According to ASCCP guidelines, what is the recommended follow-up for a cytology result of ASCUS and a negative HR-HPV test?
Repeat co-testing in 3 years
Most malignancies occurring in the renal pelvis tend to be what type?
High grade urothelial carcinoma
What often must a cytotechnologist perform proficiency testing to maintain certification?
Annually
Immunostain used to indicate breast primary
GATA-3
What solution can be used to dissolve a ferruginous body?
Bleach
Patient is a 24 y.o. female, 1 week post-partum. Assuming for a normal maturation index, what is the predominant cell type present on her pap test?
Parabasal
Voided urine of a 60 y.o. male with a hx of TCC shows scattered large polygonal cells, some of which are multi-nucleated. Nuclei are large nuclei with occasional atypia in the chromatin. What is the most likely diagnosis?
NHGUC
A cytotechnologist with 5 years experience has a daily quota set at 80 slides. They are now using the ThinPrep Imager Review Scope and screen 120 slides, 20 of which a full manual review was performed over an 8 hour timeframe. Did this cytotechnologist stay within screening limit guidelines?
Yes
Kidney / Renal cell carcinoma
What is the artifact in which air pockets are trapped under the coverslip causing brownish spots that preclude viewing of the cells underneath?
Cornflaking
The most likely reason for glandular cells appearing on a vaginal pap sample is what?
Vaginal adenosis
What is the most common malignancy that occurs in the liver?
Metastatic disease
What is the proper order to don and doff PPE including eyewear, gloves, and a labcoat?
Don - Coat, gloves, eyewear
Doff - Reverse