The combination of these two antibodies gives the greatest specificity for the diagnosis of rheumatoid arthritis.
Anti-cyclic citrullinated peptide antibody and rheumatoid factor.
What is the treatment of choice for diabetes in pregnancy?
Insulin.
What is the recommended door to balloon time by ACC/AHA for ACS?
90 minutes
Name the formula used to determine if AKI is pre-renal or post-renal.
FeNa.
The invention of what in 1666 allowed doctors see disease-causing organisms?
Microscope.
In patients with gout who require urate-lowering therapy, what is a viable alternative for those who have an adverse reaction to allopurinol?
Febuxostat.
What class of diabetic drugs promote the highest weight loss?
GLP-1 receptor agonists.
What is a genetic cause of sudden cardiac death with RBBB and ST elevation in V1-V3?
Brugada syndrome.
What is the approximate 5 year survival rate of a patient who begins hemodialysis today (assuming no other competing illness)?
35%
What percentage of the population was killed in Europe and Asia because of the Bubonic Plague?
75%.
What three characteristics are pathognomonic for Felty syndrome?
Rheumatoid arthritis, neutropenia, and splenomegaly.
What class of diabetes drugs have an FDA warning for causing euglycemic ketoacidosis?
SGLT-2 inhibitors
Taking lithium during the first trimester of pregnancy can result in this cardiac abnormality.
What agents are recommended to prevent contrast-induced nephropathy?
Hydration and supportive care (no drugs recommended).
How many body humors did the Romans believe had to be balanced?
Four. Black bile, yellow bile, phlegm, and blood.
Name the four major seronegative spondyloarthropathies.
Psoriatic arthritis, ankylosing spondylitis, inflammatory bowel disease, and reactive arthritis.
SGLT-2 inhibitors
What are the two high-intensity statins and their dosages?
Atorvastatin 40-80mg and rosuvastatin 20-40mg.
What drug has been shown to slow down decline in autosomal dominant polycystic kidney disease (ADPKD)?
Tolvaptan.
Who was the glass-blower/physicist who invented the thermometer?
Gabriel Fahrenheit.
Name 6 antibodies associated with SLE. What is the most sensitive and what is the most specific?
ANA (most sensitive), anti-Sm (most specific), anti-dsDNA, lupus anticoagulant, anticardiolipin IgM/IgG, anti-beta2-glycoprotein1, anti-Ro/SSA, anti-La/SSB, anti-U1 RNP.
Name the landmark trial in 2009 that showed intensive glucose control increased mortality in ICU patients.
NICE-SUGAR trial.
What are the 5 components that make up the HEART score?
History, EKG, age, risk factors, initial troponin.
What is the imaging modality of choice for asymptomatic microhematuria workup?
CT urography.
In 1796, who developed the first vaccination to prevent the spread of small pox?
Edward Jenner.