Helicase, Please!
5’ to 3’ and Me
RNA? I Hardly Know Ya!
From Code to Couture
Mitose-ly Speaking
100

This enzyme unwinds the DNA double helix at the replication fork.

What is helicase?

100

DNA polymerase can only add nucleotides in this direction.

What is 5’ to 3’?

100

The enzyme responsible for synthesizing RNA from a DNA template.

What is RNA polymerase?

100

The three-nucleotide sequence on mRNA that codes for an amino acid.

What is a codon?

100

This phase of the cell cycle is when DNA replication occurs.

What is S-phase?

200

DNA replication is described as this because each daughter molecule contains one original strand.

What is semiconservative replication?

200

The two strands of DNA run in opposite directions; this arrangement is called this.

What is antiparallel?

200

The DNA strand used to make mRNA is called this.

What is the template strand?

200

The molecule that carries amino acids to the ribosome.

What is tRNA?

200

This phase of mitosis is when sister chromatids separate and move to opposite poles.

What is anaphase?

300

The short DNA fragments synthesized on the lagging strand are called these.

What are Okazaki fragments?

300

The grouping of 3 bases on mRNA are the ____ and the grouping of 3 bases on tRNA are the ____.

What are codon, anticodon?

300

In RNA, thymine is replaced with this nitrogenous base.

What is uracil?

300

The site of protein synthesis in the cell.

What is the ribosome?

300

This structure holds sister chromatids together until they are separated.

What is the centromere?

400

This enzyme replaces RNA primers with DNA nucleotides.

What is DNA polymerase?

400

The nitrogenous base that pairs with adenine in DNA.

What is thymine?

400

In eukaryotes, these noncoding regions are removed before mRNA leaves the nucleus.

What are introns?

400

The codon that signals the start of translation.

What is AUG (methionine)?

400

DNA replication must occur before this major event in the cell cycle to ensure genetic continuity.

What is mitosis?

500

This enzyme seals breaks in the sugar-phosphate backbone after replication.

What is DNA ligase?

500

The structural feature that explains why one strand replicates continuously and the other discontinuously.

What is antiparallel orientation (or opposite strand polarity)?

500

This sequence in DNA signals RNA polymerase where transcription should begin.

What is a promoter?

500

A mutation that changes one amino acid but not the overall reading frame is called this.

What is missense?

500

This checkpoint ensures that DNA has been fully and accurately replicated before the cell enters mitosis.

What is the G2 checkpoint?

M
e
n
u