1
B Cell receptor is made up of?
IgM, Ig(alpha), Ig(beta) chains
Naive B cells evolve into what type of cell in the adaptive immune response?
Highly active plasma cells
IgE’s main function is to defend us from what? (Hint: you eat bad sushi, what do you correlate bad sushi and stomach ache with)
Parasite infections
IgE mainly found where?
Connective tissue
Bacterial toxins that commonly affect us are referred to as secreted and non-secreted toxins. What is the name for these toxins? (Hint: In/Out)
Endotoxin and exotoxins
Do centrocytes with high affinity receptors survive and become plasma cells?
Yes
Transcytosis and endocytosis
Name of the area where B cells and TFH cell proliferates
Germinal Center
Where are IgG and dimeric IgA predominately in?
Extracellular fluid
Interactions between which two cells are critical for survival of B cells?
B cells and follicular dendritic cells
Most disease causing bacterial infections at mucosal surfaces are prevented by?
Neutralizing antibodies — remember they coat viruses and inhibit it’s attachment to human surfaces
Isotype switching diversifies antibody function by:
changing the heavy chain C region
Interaction of B cell CD40 and TFH Cell CD40 ligand gives rise to?
B Lymphoblasts (plasmablasts)
What does the germinal center contain? (ex: zones)
Mantle zone, centroblasts, Dark zone, light zone, & centrocytes
What is the main job of monomeric IgA, IgG, and IgM?
They protect the internal tissues and prevent blood borne diseases