A
Which part of hemostasis involves the coagulation cascade?
Secondary Hemostasis
Factors XII, XI, IX, and VIII
What are the factors involved in the intrinsic pathway?
Factor III and VII
What are the factors involved in the extrinsic pathway?
Factors XIII, X, V, II, and I
What factors are involved in the common pathway?
Factor IV
Factors II, VII, IX, X
What factors are Vitamin K dependent?
TF-VIIa complex with calcium
What activates Factor X via the extrinsic pathway?
Exposed subendothelial collagen/Negatively charged surfaces, Kallikrein, and HMWK (high molecular weight kininogen)
What 3 things directly activate Hageman Factor?
What reactions is thrombin involved in?
XIII to XIIIa
VIII to VIIa
V to Va
I to Ia
Fibrin Stabilizing Factor
What is another name for Factor XIII?
If blood is placed into an empty untreated test tube, what pathway will it primarily clot through?
Intrinsic
What factor is VWF bound to?
Factor VIII
What factor has the shortest half-life?
Factor VII
Va, Xa, Phospholipid, and Calcium
What makes up the prothrombinase complex?
What steps require calcium?
TF-VII activity
IX, X (int and ext), and II activation