Gene Therapy
Pros & Cons
History
100
What is Gene therapy ?
It is a new technique that is used to fix gene disease, changing abnormal genes to normal ones.
100
Name 2 disadvantage of gene therapy.
It is very expensive. It is still developing, any error in finding the precise location of the defected gene, could cause a risk of new disease.
100
When did Gene Therapy research began ?
They began researching in 1972 .
200
Name at least 2 techniques used for Gene Therapy.
A normal gene may be inserted into a nonspecific location within the genome to replace a nonfunctional gene. This approach is most common. An abnormal gene could be swapped for a normal gene through homologous recombination. The abnormal gene could be repaired through selective reverse mutation, which returns the gene to its normal function. The regulation of a particular gene could be altered.
200
Name 2 advantages of Gene Therapy
It can wipe out genetic disease. Eliminate suffering for future generations.
200
What is the name of the institution that was first successful in Gene Therapy ? Hint: NIH
National Institute of Health
300
Name 3 types of viruses used for Gene Therapy.
Adenoviruses Retroviruses Herpes simplex virus
300
Name at least 2 of the 4 things that stops Gene therapy from being effective.
Short-lived nature of gene therapy Immune response Problems with viral vectors Multigene disorders
300
Fill in the blank: In 2011 a man was cured of _____using gene therapy.
HIV
400
What is a vector ?
It is a type of virus inserted into the body, to cure disease.
400
Is it possible that a superior race can be formed ?
Some people are concerned that gene therapy will be used to create a superior race. This is not the goal of the geneticist.
400
Which journal reported that researchers succeeded at halting ALD ?
Science Journal
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