Structure/Location
How many 6 carbon rings are in a steroid nucleus?
3
Which ring of the the steroid skeleton is broken by UVB radiation in Vitamin D synthesis?
B
Which cells of the body does T4 target?
Most cells
What mineral cannot be absorbed as well if vitamin D is deficient?
Calcium
What does the "R" stand for in MRI?
Resonance
Name the enzyme in the kidney that catalyzes the last step to create active vitamin D?
1-alpha-hydroxylase
Name one effect
If there is high ACTH in blood, will cortisol increase, decrease or stay the
What is the term that describes ALL potential causes of hypercortisolism?
What structural class do TRH and CRH fall into?
Peptide
What enzyme couples together DIT and MIT to make T3?
Thyroid peroxidase
What layer of which organ does ACTH act on?
Zona fasiculata
If blood calcium is high, does PTH increase, decrease, or stay the same?
Decrease
What auto-immune disease leads to antibodies against some of the enzymes/proteins the are part of building T3/T4?
Hashimoto's thyroiditis
Calcitonin
Thyroid
In what structural location are full
Colloid
Name an organ that PTH targets.
Kidney and bone
If cortisol decrease in blood plasma, will ACTH increase, decrease, or stay the same?
Increase
Osteomalacia
What type of bond forms between the two aromatic rings in T4?
Ether bond
What transporter creates an energy gradient that powers the Na+I- symport to be able to transport I- into follicular cells?
Na+K+ ATPase
Name the effect cortisol has in the body that causes
Gluconeogenesis
If someone has high T4, high TSH, and high TRH and has a tumor, where is the tumor most likely located?
The hypothalamus
The three main components of a radioimmunoassay are 1) the radio-labeled antigen, 2) the antigen from plasma, and 3) _______________.
An