Amino Acids
Neuropeptides
Purines
Pharmacokinetics
Pharmacodynamics
100

What is the most abundant amino acid in the brain?

Glutamate

100

Name 3 neuropeptides

endorphins, substance p, enkephalins 

100

What are the two kinds of Purines?

Exogenous and Endogenous 

100

Medications administered intravenously are nearly __% bioavailable

100%

100

Pharmacodynamics refers to the drug's effect on the ____?

Body

200

What Amino Acid neurotransmitters are found at inhibitory synapses?

Glycine and GABA

200

What do endogenous opioids do?

Produce analgesia aka pain suppression

200

Is Adenosine excitatory or inhibitory?

Inhibitory. It acts as a CNS depressant
200

What is a major site of drug metabolism

Liver

200

What hinders neurotransmitters by blocking its release?

Antagonist

300

This regulates rapid changes in fear arousal, such as anxiety, panic, and acute stress responses

GABA

300
What does nociception cause?

The perception of pain

300

When awake, levels of _____ rise each hour.

Adenosine

300

A drug that becomes protein-bound and is so large it cannot exit the capillary is rendered ____?

Inactive

300

A drug that increases the availability or mimics the action of an endogenous NT

Agonist

400

This Amino Acid plays an important role in learning and memory

Glutamate
400

When produced from the CNS, Enkephalins do what?

Create opiate and analgesic effects

400

These purines are developed from external factors such as food

Exogenous

400

Medications that are chemically altered by liver enzymes results in the production of chemical by-products called ___?

Metabolites

400

Binding postsynaptic receptors without stimulating them

Antagonist

500

Deficiencies in this Amino Acid is related to Huntington's Disease, anxiety, and epilepsy

GABA

500

This is critical for regulation of affective behavior and neurochemical response to stress 

Substance P

500

These Purines are found within cells of all living things to aid in energy transport

Adenosine Triphosphate

500

A client with kidney problems may accumulate more/less drugs in the body?

More

500

Methadone is an agonist or antagonist?

Agonist

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