Largest organ in the body?
Skin
First stage of wound healing?
Hemostasis
What color change signals inflammation?
When does the proliferation stage begin?
2-3 days after injury
Last stage of healing?
Remodeling(Maturation)
Outer protective layer of the skin?
Epidermis
What happens to blood vessels to reduce bleeding?
Vasoconstriction
Main immune cells that "eat/consume" pathogens?
Macrophages
Cells that move in to build new tissue are called..
Fibroblasts
How long can remodeling take?
Over a year
Main cells in the epidermis?
Keratinocytes
What forms to seal the wound and block pathogens?
Blood clot
Why is inflammation important?
Kills pathogens and removes debris
Fibroblasts deposit what protein?
Collagen
What is the range by how much function can healed skin recover to its original self?
50-80%
Middle skin layer containing blood vessels, glands, nerves?
Dermis
Why is hemostasis critical?
Stops bleeding & prevents infection
Process macrophages use to get rid of bacteria?(consuming debris, dead cells, and pathogens)
Phagocytosis
What replaces fibrin during proliferation?
Connective Tissue (Collagen)
Why is scarring common?
Skin does not fully recover at times
Protein that makes skin tough and protective?
Keratin
Protein forming cross-links to seal the wound?
What happens to blood vessels during inflammation (opposite of vasoconstriction)?
Vasodilation
What do epidermal cells do during proliferation?
Divide to reform skin
One mystery about wound healing in humans?
Origin of fibroblasts or why animals like deer heal better.