Immunology of Infection
Opportunistic Infections
Common Opportunistic Infections in HIV
PJP
HIV Prevention
100

HIV enters the cells by...

What is binding to the CD4 molecule on the surface of the lymphocyte?

100

What has decreased the incidence of OIs?

What are anti-retrovirals?

100

What pathogen is responsible for Oral Hairy Leukoplakia?

What is Epstein-Barr Virus?

100

What are four common symptoms associated with PJP?

What are fever, progressive dyspnea, non-productive cough, and hypoxia?

100

Prescriptions for PrEP must not be continued beyond what period of time if an individual does not have a confirmed HIV-negative status?

What is 3 months?

200

What is the longest lasting phase of HIV infection?

What is the latent/asymptomatic phase?

200

What is primary prevention of OIs?

What is preventing 1st episode of disease?

200

What is the treatment given for Thrush?

What is Fluconazole (nystatin)?
200

What is the first line treatment for those with PJP?

What is Trimethoprim/Sulfamethoxazole PO or IV x 21 days?

200

What are the 2 drugs used for PrEP in Canada?

What are TDF/emtricitabine (Truvada) and TAF/emtricitabine (Descovy)?

300

What is the window period for HIV testing? 

What is 10 days to 4 weeks?

300

What is secondary prevention of OIs?

What is prevention of reactivation or recurrence of an infection after it has been treated?

300

When is primary prevention indicated when an individual has Toxoplasmosis?

What is when CD4 <100 and serum Toxo IgG is positive?

300

When is adjunctive therapy indicated for those with PJP?

What is when PaO2 <70 mm Hg or when A-a gradient > 35 mm Hg?

300

Following exposure, how long after should PEP be started and how long must it be taken for? 

What is less than 72 hours and for 28 days?

400

What happens to the ratio of CD8 and CD4 cells in early HIV infection?

What is it decreases?

400

When should OI prophylaxis be initiated?

What is once CD4 <200?

400

What is an episodic treatment given to those with HSV?

What is valacyclovir, famciclovir, or acyclovir?

400

How long should secondary prevention be continued in those with PJP?

What is until CD4 >200 for at least 3 months?

400

When should IV zidovudine be given during labour?

What is when viral load > 1000 c/ml within 4 weeks of delivery, unknown viral load, suspected poor adherence to medication or positive rapid HIV test?

500

Why do opportunistic infections occur when HIV load increases?

What is T cell immunity degradation?

500

What is the most common OI in North America?

What is Pneumocystis jirovecii pneumonia?

500

What is the minimum treatment time for those with Disseminated MAC?

What is 12 months?

500

What are 3 common symptoms of treatment toxicity in those with PJP?

What are rash, fever, and leukopenia?

500

What viral load status of the mother would prompt 4 weeks of zidovudine administration within 6-12 hours of birth? What about triple therapy from birth to 6 weeks?

What is VL <50 c/ml? What is VL >50 c/ml?

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