500
You are infected with a bacterial disease. Your sister had this same illness last week, and
took a full cycle of antibiotics. She quickly became better. You started taking the same
antibiotic, but they had no effect. In fact, you had to return to the doctor after a week,
because you did not feel better. What has happened? Why did you remain sick after
taking antibiotics, while your sister quickly recovered? There are three possible
hypotheses:
A) you developed a tolerance for the antibiotic (i.e. you experienced a non-genetic
change that made you less sensitive to the effects of the antibiotic).
B) the bacteria infecting you developed a tolerance for the antibiotic (i.e. individual
bacteria experienced a non-genetic change that made them less sensitive to the
effects of the antibiotic).
C) the bacteria infecting you evolved to be resistant to the antibiotic (i.e. a genetic
mutation for resistance occurred in a bacterial cell, it had a reproductive
advantage and increased in the population).
B) the bacteria infecting you developed a tolerance for the antibiotic (i.e. individual
bacteria experienced a non-genetic change that made them less sensitive to the
effects of the antibiotic).