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100

Pembrolizumab and ipilimumab are examples of this therapeutic class

What are checkpoint inhibitors

100

Name two of the classic nephrotic diseases?

Minimal change, FSGS, membranous, membroproliferative, diabetic nephropathy, amyloid nephropathy
100

For for the first time in several months, this person was seen publicly alongside Jill Biden on Mother's Day

Olena Zelenska (first lady of Ukraine)

100

Interventional cardiologists may sometimes infuse abciximab, tirofiban, or eptifibatide alongside ASA peri-PCI in patients who might not tolerate P2Y12 inhibitors or high risk of thrombus. What class do these drugs belong to? 

Glycoprotein (GP) IIB/IIIA inhibitors 

100

Causative agent in 80% of cases of septic arthritis

Staph Aureus

200

Name this illness script: facial flushing, leathery skin, chronic smoker, and headache

What is SVC syndrome/pancoast tumor

200

Approximate 5 year survival rate of a patient who begins hemodialysis today (assuming no other competing illnesses) +/- 10%

What is 35%

200

When Elon Musk first attempted to buy Twitter, board members used this business tactic to ward him off (temporarily) 

Poison Pill

200
Criteria to assess MI in the setting of a LBBB
What is Sgarbossa's criteria?
200

What is the first line therapy for fibromyalgia treatment that results in fewer subspecialty referrals

Regular aerobic exercise

300

Name two of the three most common sites of metastasis in malignant melanoma

What is CNS/Brain, Lung, Liver

300
Agents recommended to prevent CIN - contrast induced nephropathy (after LHC, etc)
What is hydration and supportive care (no drugs recommended)
300

Dr. Gladwin will be serving as Dean of this medical school starting August 1

University of Maryland

300

HOCM, long-QT, WPW, and Brugada syndrome are all predisposing conditions of what?

Sudden cardiac death

300

A 28-year-old woman seeks preconception counseling. She has a 4-year history of systemic lupus erythematosus (SLE) with manifestations of photosensitive rash, arthritis, and pericarditis; she has been treated with hydroxychloroquine and low-dose prednisone with good control of her symptoms for 18 months. Her SLE labs show ANA (1:1320), positive anti-Ro/SSA antibodies, and negative anti-U1, anti-dsDNA, and anti-Smith antibodies. She is counseled about the increased risk of preeclampsia and preterm delivery. Based on her antibody profile, identify the most important additional risk to the fetus to counsel her about.

Risk of congenital heart block in her baby

400

When monitoring for TLS, all lab values are expected to be elevated EXCEPT for:

What is calcium

400

Name the three most helpful labs for working-up hyponatremia

Sosm, Uosm, UNa
400

At a near 40-year high, _________ stabilized this week at 8.3%

Inflation

400

Beta-blockers and ARNI/ARB or ACE/ARB are first-line GDMT for HFrEF (<35%) patients. What two other drugs are part of the HFrEF GDMT algorithm?

Aldosterone antagonists and SGLT2i

400

Name the four most common seronegative polyarthropathies 

Psoriatic arthritis, IBD-related, Reactive arthritis, Ankylosing Spondylitis 
500

Name two cancers for which checkpoint inhibitors (immunotherapy) are now first line treatment

Advanced NSCLC, RCC, melanoma
500
Rare virus causing kidney injury in later stages in post-transplant patients
What is Polyoma BK virus?
500

Despite a last-minute plea to “respectfully bow out” of contention for the Rock & Roll Hall of Fame, the country singer __________  was voted in anyway.

Dolly Parton 

500

What HR-lowering drug can be added alongside HFrEF GDMT in patients already on maximally dosed B-blockers

Ivabradine

500

Most common antibody directed against histidyl–tRNA synthetase

Anti-Jo1

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