Immune System
Virulence, Infection, Pathogenicity
Exotoxins
Miscellaneous
Modules 1-3 Review
100

X-linked agammaglobulinemia is a type of this immunodeficiency.

What is a congenital immunodeficiency?

100

This describes a bacteria's ability to cause harm.

What is pathogenicity?


For extra points, what is virulence?

100

This type of anthrax is the "deadliest".

What is pulmonary anthrax?

100

This describes something a patient tells you, rather than something you see.

What are symptoms?

100

These are the inclusions that can be found in bacteria.


What are gas vacuoles and magnetosomes?


For extra points, what are the storage inclusions?

200

This immunoglobin is released first in a primary antibody response.

What is IgM?

200

Strain A has an LD50 of 2000.

Strain B has an LD50 of 3000.


This one is more deadly.

What is Strain A?

200

These exotoxins only become a toxin when it is in contact with a bacteriophage.

What is diphtheria and botulism?

200

T or F: Toxoids do not typically cause harm and are often the basis of vaccines.

What is true?

200

Which of the following is a carbon skeleton produced in EMP?

A. Oxaloacetate

B. Glyceraldehyde 3-phosphate

C. Succinate

D. Ribose 5-phosphate

E. Acetyl-CoA

What is B, Glyceraldehyde 3-phosphate?

300

Which of the following is NOT a direct function of antibodies?

A. Opsonization

B. Destruction

C. Neutralization

D. Precipitation

E. Complement fixation

What is B, destruction?

300

This describes a disease that goes from animal to human.

What are zoonoses?

300

This type of exotoxin alters the permeability of the intestinal epithelium.

What are enterotoxins?


For extra points, what are the different ways to get enterotoxins?

300

This is the causative agent of the plague.

What is Y. pestis?

300

These 2 amino acids have a sulfur in their R group.

What are cysteine and methionine?

400

Which of the following characteristics accurately describes the secondary antibody response?

A. Longer lag phase

B. High IgM titer, low IgG titer

C. Basis of vaccine

D. Lower affinity, higher avidity

E. None of the above

What is C, basis of vaccine?

400

This bacteria uses actin rockets to spread virulence factors.

What is Listeria monocytogenes?

400

Which of the following is true regarding tetanus?

A. It is produced by a Bacillus species.

B. It is the most potent biological toxin known.

C. It blocks the release of acetylcholine, causing flaccid paralysis.

D. B and C

E. None of the above.

What is E, none of the above?

400

LSD is an example of this type of toxin.

What is a mycotoxin?

400

This structure is present in both penicillin and carbapenem.

What is a β-lactam ring?

500

Which of the following are characteristics of IgG?Select all that apply:

A. Can cross the placenta

B. 1 is required to activate the complement system

C. Performs opsonization, but not neutralization

D. Has 10 binding sites

E. Has high affinity, but low avidity

What is A and E?

500

Which of the following is true regarding virulence factors? Select all that apply:

A. They typically release enzymes out into the environment.

B. Pathogenicity islands are transferred through vertical gene transfer.

C. Coagulase and fibrinolysin perform similar functions.

D. Leukocidins kill red blood cells.

E. Hyaluronidase is also known as the spreading factor.

What is A and E?

500

Which of the following are characteristics of exotoxins?

A. Only produced by Gram-positive bacteria

B. Soluble and heat-stable

C. Includes cholera

D. Highly immunogenic

E. Includes both enterotoxins and endotoxins

What is C and D?

500

Which of the following statements is true?

Select all that apply:

A. Superantigens cause an exaggerated immune response that stimulates B cells.

B. IgA is secreted in breast milk.

C. The tetanus and botulism toxins are neurotoxins.

D. Clostridium perfringens is found in anoxic conditions.

E. Septic shock is associated with severe hypertension.

What is B, C, and D?

500

This enzyme initiates the CAC; and produces acetyl-CoA and CO2.

What is pyruvate dehydrogenase?

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