Immunity & Inflammation
Immune system cells have proteins on their surface that allows the body to identify the difference between its own healthy cells and non-self protein antigens.
RA primarily affects this part of the body.
What are synovial joints?
SLE primarily affects the cells that make up this type of tissue.
What is connective tissue?
True or False: Children with JIA have a negative rheumatoid factor 90% of the time.
What is true?
These are the different stages of HIV.
What is
⚫Stage 1- Acute (Short)
⚫Stage 2- Chronic (Years to decades)
⚫Stage 3- AIDS (Significantly decreased CD4 count parameters and presence of an opportunistic infection)
This is a process where an inappropriate immunity develops to an adults own tissues.
What is autoimmunity or an autoimmune disorder?
These are late symptoms of RA.
What is increased inflammation and pain, morning stiffness, joint deformity, and skin lesions/nodules?
This is a type of lupus that is not systemic and only affects the skin.
What is discoid lupus?
(Chronic cutaneous lupus erythematosus (CCLE) which is often characterized by a discoid (disk shaped) rash)
JIA is characterized by these symptoms.
What is joint pain, tenderness, and edema which can cause limping? Some systemic sx include fever, rashes, and delayed growth.
This lab finding is significant in the diagnosis of AIDS.
What is a CD4 count less than 200 cells/mm3?
Infections that occur more frequently or are more severe in individuals with weakened immune systems.
What is an opportunistic infection?
This is a life threatening complication of RA.
These are a group of autoantigens that can be found in the nucleus of cells. Testing of these is important in the diagnosis and management of various autoimmune diseases such as SLE.
What are extractable nuclear antigens (ENAs)?
⚪anti–SS-a (Ro)
⚪anti–SS-b (La)
⚪anti-Smith (anti-Sm)
⚪anti-dsDNA
These are complications of JIA.
What is uveitis/blindness, Growth Retardation, Joint deformity, & Functional disability?
These are ways HIV can be transmitted.
What is sexually, parenterally, and perinatally?
A significant decrease in these lymphocytes can indicate immunosuppression and increased susceptibility to infections.
What are CD4 cells?
This is a very specific and sensitive test to detect RA in the early stages, but it is also a marker for aggressive and erosive late-stage disease depending on the level.
What is anti-cyclic citrullinated peptide (anti-CCP)?
This medication used to treat SLE reduces B lymphocytes ability to produce autoantibodies.
What is Belimumab (Benlysta) monoclonal antibody therapy?
These are nursing considerations to manage symptoms of JIA.
What is manage fatigue, pain control, stress management, and mobility aids?
This class of medications works by altering the DNA and RNA of cells to prevent viral replication at different stages in the HIV life cycle; this can help to slow disease progression and improve life span.
What is combination antiretroviral therapy (cART)?
This is a non-specific and protective syndrome of normal tissue responses to cellular injury, allergy, or invasion of pathogens. It is an important part of general immunity.
What is inflammation?
This intervention completely removes the inflamed lining of an RA affected joint.
What is a synovectomy?
This is the leading cause of death in patients with SLE.
What is kidney damage (lupus nephritis & CKD)?
This is an important assessment to identify a life altering diagnosis in patients with JIA.
What are regular vision screenings?
These are nursing considerations that are important to educate patients with HIV/AIDS about.
What is strict medication adherence, pain management, prevent infections, prevent the spread of disease, nutrition, and psychosocial preparations.