Body Fluids
T/F Decreases CSF glucose levels can indicate acute bacterial meningitis
True
Name 2 factors that influence drug concentrations and efficacy.
age, gender, genetics, diet, co-administered drugs, naturopathic agents
What lipophilic drug is also known as "angel dust"
Phencyclidine (PCP)
This tumor marker is often elevated in patients with hepatocellular carcinoma and germ cell tumors.
alpha fetoprotein (AFP)
What CSF collection tube should chemistries be performed on?
Tube 1
What term is used to describe the collection method of pleural fluid?
Thoracentesis
Weak bases are absorbed in the _____
intestine
What type of drugs are used to treat depression and mood disorders and are named for their chemical structure?
Tricyclic antidepressants (TCAs)
Which tumor marker has both free and bound forms that can be measured to help assist in risk stratification?
Prostate Specific Antigen (PSA)
What is the generic term for aspirin?
Acetylsalicylic acid
Monosodium urate crystals are seen in the synovial fluid with what disease state?
Gout
Changes in concentration of this protein affects free vs bound drugs.
Albumin
Positive drug screens for this type of substance has wide cross-reactivity with common OTC medications.
Amphetamines/Methamphetamines
Elevated levels of this tumor marker post treatment for ovarian cancer indicates a poor prognosis.
CA-125
This potent inhibitor of many enzymes may cause basophilic stippling in RBCs.
Lead
What test can be performed to determine if the fluid coming from a patient's nose is sinus or spinal fluid?
Beta-transferrin
1.1 ug/mL
10% free, 90% bound
If a person consumes alcohol at the same time as taking this drug, there is a higher risk of hepatic damage
Acetaminophen
This test is not actually cleared by the FDA as a tumor marker even though there is widespread use of it as one.
Human Chorionic Gonadotropin (hCG)
highly hydrophobic
CSF total protein is considered to be what percentage of the total blood protein value?
0.5-1.0%
This is the biochemical pathway responsible for a large portion of drug metabolism.
Hepatic mixed-function oxidase system (MFO)
This toxin is found in solid, liquid, and in solution. It binds to heme iron and high lactic levels are common.
Cyanide
This tumor marker is primarily used for ovarian cancer and has improved specificity over CA-125
This tumor marker is a modified Lewis blood group antigen.
Carbohydrate antigen 19-9 (CA 19-9)