Types
Also know as kiddie coke
Methylphenidate (Ritaline)
Blocks membrane transporters for monoamines and increases DA transport into vesicles
Cocaine
Purposeless behavior in humans after consuming high doses of a psychostimulant
Punding
These type symptoms characterize psychostimulant withdrawal (or this type of dependence).
Psychological
Caffeine
Derived from Nicotiana tabacum
Nicotine
Blocks adenosine receptors
Caffeine
Psychostimulant induced tactile hallucination is characterized by feeling of insects crawling underneath the skin.
Formication
Lack of dental hygiene, consuming lots of sugary drinks, and enhanced sympathetic nervous system activity often leads to this.
Meth mouth
People with the C-1021T polymorphism are more likely to have negative subjective effects from taking psychostimulants and less likely to be chronic users. This polymorphism probably achieves this by lowering the levels of this enzyme.
Beta-hydroxylase
Caffeine, theobromine, and theophylline
Xanthines
Causes monoamine transporters to run in reverse and displace DA in synaptic vesicles
Amphetamines
Behavioral testing procedures used to distinguish the subjective effects of drugs.
Drug discrimination procedures.
Repeated use of psychostimulants leads to sensitization of these types of behaviors.
Purposeless
This drug is also used to treat alcohol addiction but may also be used to increase negative subjective effects in psychostimulant abusers by blocking beta-hydroxylase activity.
Disulfiram
Although mass produced in 'crystal labs' users often prefer the freebase version of this psychostimulant
Cocaine (or crack cocaine)
These two drugs resemble but have weaker efficacy than amphetamines
Methylphenidate and Cathinones
Weaker nicotine effects on heart rate and blood pressure after a single nicotine administration.
Acute tolerance
Rodents in an open-field apparatus will initially show low levels of this after first consuming nicotine, but, over time we observe sensitization for this.
Locomotor activity (increased psychomotor function)
These people fail to develop an addiction to tobacco.
Chippers
You definitely do not want to take a 'bath' with these (Looking for the scientific (chem) name, not the street name)
Cathinones (aka bath salts)
Tobacco consumption increases DA release in the NA from nicotine binding to and activating ACh nicotinic receptors. Other chemicals in tobacco increase DA concentrations in the NA through this mechanism.
Inhibition of MAO enzymes
Nonsmokers typically feel these types of subjective effects, such as disequilibrium and nausea, after a single administration of nicotine.
Negative
Example of cancer causing agents found in tobacco.
Nitrosamines
Reaching this many weeks of smoking abstinence is the strongest predictor for long-term success.
2 weeks