Diagnosis/Disease
Common Treatment
Most Common/Important Associations
Equation
Diagnosis/Diseases
100

Calf pseudohypertrophy


Muscular dystrophy (most commonly Duchenne, due to X-linked recessive frameshift mutation of dystrophin gene)


100

Stable angina


Sublingual nitroglycerin


100

Hypopituitarism


Pituitary adenoma (usually benign tumor)


100

Relative risk



RR = a/(a + b) over c/(c + d)


100

Hair on end” (“crew cut”) appearance on x-ray


β-thalassemia, sickle cell disease (marrow expansion)


200

Child uses arms to stand up from squat


Duchenne muscular dystrophy (Gowers sign)


200

Streptococcus bovis


Penicillin prophylaxis; evaluation for colon cancer if linked to infective endocarditis


200

Cushing syndrome



Iatrogenic (from glucocorticoid therapy); Adrenocortical adenoma (secretes excess cortisol); ACTH-secreting pituitary adenoma (Cushing disease); Paraneoplastic (due to ACTH secretion by tumors)

200

Number needed to harm


NNH = 1/AR


200

“Onion skin” periosteal reaction


Ewing sarcoma (malignant small blue cell tumor)


300

Dilated cardiomyopathy/high-output heart failure, edema, alcoholism or malnutrition


Wet beriberi (thiamine [vitamin B1] deficiency)


300

Hyperaldosteronism


Spironolactone


300

Tumor of infancy


Strawberry hemangioma (grows rapidly and regresses spontaneously by childhood)


300

Sensitivity


Sensitivity = TP / (TP + FN)


300

“Tram-track” appearance of capillary loops of glomerular Membranoproliferative glomerulonephritis basement membranes on light microscopy


Membranoproliferative glomerulonephritis


400

Microcephaly, high-pitched cry, intellectual disability


Cri-du-chat (cry of the cat) syndrome


400

Recurrent UTI prophylaxis


TMP-SMX


400

Type of non-Hodgkin lymphoma (most common)


Diffuse large B-cell lymphoma


400

Stroke volume


SV = EDV – ESV


400

Cellular crescents in Bowman capsule


Rapidly progressive (crescentic) glomerulonephritis


500

Bounding pulses, wide pulse pressure, diastolic heart Aortic regurgitation 298 murmur, head bobbing


Aortic regurgitation


500

Malaria


Chloroquine, mefloquine (chloroquine resistant cases), 154 atovaquone/proguanil, primaquine (for liver hypnozoite)


500

Nephrotic syndrome (children)


Minimal change disease


500

Relative risk reduction


RRR = 1 − RR


500

Podocyte fusion or “effacement” on electron microscopy


Minimal change disease (child with nephrotic syndrome)


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