Depression 101
At least 5 of these symptoms must be present during the same two week period to be diagnosed with depression.
What is
Energy - decreased
Sleep - increased/decreased
Concentration - decreased
Appetite - increased/decreased
Psychomotor agitation/retardation
Interest/pleasure - diminished
Suicidal ideation
Mood -depressed
Guilt or feelings of worthlessness
ESCAPISM G
This is the generic and brand name of an MAOI.
What is Isocarboxazid [Marplan] or
Phenelzine [Nardil] or
Tranylcypromine [Parnate]
These types of food should be avoided with MAOIs because it can increase risk of hypertensive crisis/serotonin syndrome.
What are tyramine-rich foods?
This SSRI is preferred for patients with cardiac risk.
What is sertraline?
This medication may be considered for patients requiring an antidepressant who also experiences generalized anxiety disorder, panic disorder or social anxiety.
What is venlafaxine?
The symptoms of serotonin syndrome. (At least 4)
What is Severe nausea, Dizziness, Headache, Diarrhea, Agitation, Tachycardia, Hallucinations or Muscle rigidity?
The 5 G's that increase bleeding risk when combined with SSRIs and SNRIs. (Natural products)
What is Garlic, Ginseng, Ginger, Ginkgo and Glucosamine?
These medications should be taken at bedtime to prevent daytime sedation.
SSRIs when combined with MAOIs can increase the patient's risk of hypotensive crisis or serotonin syndrome and therefore requires a 2-week washout period. This medication is the one exception.
What is fluoxetine.
Fluoxetine requires a 5 week washout period due to its long half-life.
This must be given with every antidepressant that is dispensed.
What is a MedGuide?
What is St. John's wort, SAMe (S-adenosyl-L-methionine), 5-HTP (5-hydroxytryptophan) and Valerian?
This tertiary amine has a brand name formulation that is approved for insomnia. Bonus $50: What is the brand name?
What is doxepin?
Bonus $50: Silenor
The time it takes for physical symptoms to improve after antidepressant use.
What is 1-2 weeks?
The warning regarding SSRI use during pregnancy?
Usually prescribed to patients experiencing sexual dysfunction with traditional antidepressants.
What is bupropion or mirtazapine?
It is important to rule out these two conditions before starting antidepressant therapy.
What is Bipolar disorder & Anxiety
This SSRI/olanzapine combination product can be used for treatment-resistant depression. [Brand name?]
What is Symbyax?
This side effect may be heightened in some children, teenagers or young adults within the first few months of treatment or when the dose is changed.
What is an increase in suicidal thoughts or actions?
These side effects are present in SNRIs due to their affect on norepinephrine.
What is increased heart rate, dilated pupils, dry mouth, excessive sweating and constipation?
This medication is commonly used in oncology and skilled nursing facilities to help with sleep and increase appetite.
What is mirtazapine?
Treatment with antidepressants should be done over this period of time before deemed that it is ineffective.
This medication is also approved for treatment of peripheral neuropathy, fibromyalgia, GAD and chronic muscoskeletal pain.
What is duloxetine?
The max dose of escitalopram that can be taken per day in elderly to prevent risk of QT prolongation
What is 10 mg/day
These three drugs can cause metabolic issues including dyslipidemia, weight gain and diabetes.
What is aripiprazole, olanzapine and quetiapine?
These 3 SSRIs are also approved for Premenstrual Dysphoric Disorder (PMDD).
What is Fluoxetine, Paxil CR and Sertraline?