Asthma Peter Jones
Anatomy
spirometry/anatomy
PES
Pharm
100

what are two examples of Beta agonist bronchodilators?

salbutamol 

terbutaline (bricanyl)

100

At which ribs does the diaphragm end anteriorly, posteriorly and in the axillary. 

6. 8. 10. 

100

What portion of the respiratory system intiates the gag/cough reflex?

Carina - very sensitive, this is the the part when the trachea bifurcates into left and right main bronchus

100

Does food get stuck in the right or left main bronchus? and why?

 right because it is more vertical

100

Which division of the autonomic nervous system predominates in controlling bronchioles?

Parasympathetic

200

What is tachyphylaxis 

A high intensity prolonged stimulus or repeated stimulus that can cause a diminished response known as desensitisation

200

The anterior axillary line is bordered by the pectoralis major. The posterior axillary line is formed by the.......

Latissimus dorsi and teres major

200

Can both plerual linings be dissected from the lungs?

 nO, THE visceral plerua cannot be dissected

200

what happens to FVC and FEV1/FVC ratio in restrictive

FVC is reduced FEV1/FVC ratio is similar

200

 Where is the resistance to airflow greatest in the respiratory system?

Bronchi near trachea

300

6 puffs of Ventolin via a spacer = ??? through a Ventolin nebule

2.5 mg Ventolin nebule

300

which types of cells produce surfactant in the alveoli 

Type 2 pneumocytes

300

what happnes to lung elasticity and compliance during emphysema

 compliance increases elasticity decreases

300

what Are the 3 types of Horners syndrome and describe each one

miosis

partial ptosis 

anhydrosis

300

Mode of action of Cromones are?

Prevention of allergic response

400

The onset of Type 4 hypersensitivity is?

 24-72 hours

400

Bob has been transported to the Emergency Department with a suspected pneumothorax and is in respiratory distress. The ED physician determines that he needs an urgent chest drain. Where is the typical location for a chest drain to be inserted (be specific)?

Between the 5th and 7th intercostal space in the mid-axillary line (may also be done in the 4th intercostal space)

400

what happens to FEV1 and FEV1/FVC ratio in obstructive

both decreace

400

Conjunctival pallor in a resp physical examination could indicate what possible disease ? 

lung tumour in the apex 

400

what is the mode of action of leukotriene receptor antagonists and give an example

eg montelukast , saferlukast


blocks action of leukotriene D4 by inhibiting cysteinyl receptor 

500

Which of the following blood types incompatibilities between the mother and the newborn is most commonly associated with Hemolytic Disease of the Newborn (HDN) and what antibody is involved?


A) ABO incompatibility + IgG

B) ABO incompatibility + IgM

C) Rh incompatibility + IgG

D) Rh incompatibility + IgM

Rh incompatibility + IgG

500

list all the muscles that depress the ribs 

  • Innermost intercostals
  • Internal intercostals
  • Transversus thoracic
  • Subcostal muscles
500

In Type 3 Hypersensitivity reactions, which mechanism plays a significant role in the destruction of target cells or tissues?

 Formation of immune complexes

500

Wrist tenderness in PES examination is indicative of what disease?

HPOA

Hypertrophic osteoarthropathy

500

 In the context of asthma management, muscarinic antagonists (anticholinergics) are often used alongside beta2-adrenergic agonists like albuterol. How do the mechanisms of action of these two types of medications differ, and why is their combination beneficial in asthma treatment?

Muscarinic antagonists block the action of acetylcholine, while beta2-adrenergic agonists stimulate adrenergic receptors, providing complementary bronchodilation and reducing the risk of tachycardia.

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